CCDC134 Activators
CCDC134 is a protein that has been identified as playing a crucial role in several cellular processes, including cell apoptosis, immune response, and osteogenesis. As a coiled-coil domain containing protein, CCDC134 is known to interact with various other proteins and has been implicated in modulating the activation of CD8+ T cells, an essential component of the immune system's response to infection and disease. In the realm of osteogenesis, CCDC134 is thought to be involved in the differentiation and proliferation of osteoblasts, the cells responsible for bone formation. Furthermore, through its involvement in the ERK and JNK signaling pathways, CCDC134 is postulated to play a role in cell death and survival, affecting the delicate balance between apoptosis and cell proliferation.
In the quest to understand how the expression of CCDC134 might be induced or upregulated, several chemicals emerge as potential activators. Retinoic acid and vitamin D3, both involved in immune response and bone metabolism, may stimulate the production of CCDC134 by enhancing pathways associated with T cell activation and osteogenesis. Dexamethasone, a glucocorticoid, might stimulate CCDC134 expression by strengthening CD8+ T cell responses. Certain plant-derived compounds, such as curcumin, resveratrol, sulforaphane, and quercetin, which are known to modulate inflammation, apoptosis, and cellular signaling, might induce CCDC134 expression by acting on these pathways. Genistein and Epigallocatechin Gallate (EGCG), both influencing ERK signaling, could potentially upregulate CCDC134. 5-Azacytidine and Sodium Butyrate, compounds that affect broader gene expression patterns, might also increase CCDC134 production. Lastly, folic acid, integral to cellular growth and development, could stimulate the upregulation of CCDC134 considering its role in osteogenesis. Each of these chemicals provides a compelling avenue for research into the regulation of CCDC134 expression, offering insights into the complex interplay of cellular processes and pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
As a key regulator of gene expression and immune response, retinoic acid might stimulate the production of CCDC134 by enhancing pathways associated with T cell activation, where CCDC134 is known to play a role. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Given its involvement in bone metabolism and immune function, Cholecalciferol may potentially enhance the expression of CCDC134, particularly considering CCDC134's known function in osteogenesis and activation of CD8+ T cells. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
As a glucocorticoid influencing immune responses, Dexamethasone might stimulate CCDC134 expression by strengthening CD8+ T cell responses, a cellular process where CCDC134 has been shown to be active. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
(-)-Epigallocatechin Gallate, due to its inhibitory effect on ERK signaling, could potentially induce the upregulation of CCDC134, considering that both EGCG and CCDC134 appear to modulate the ERK pathway. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin, which impacts inflammation and apoptosis, might induce CCDC134 expression by stimulating pathways associated with cell death and immune responses, areas where CCDC134 has a known role. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, by influencing cellular pathways related to apoptosis and bone development, might stimulate the production of CCDC134, given its known role in these processes. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
DL-Sulforaphane, known to modulate ERK signaling and apoptosis, might promote the upregulation of CCDC134 expression by acting on these cellular pathways where both ERK and CCDC134 have been implicated. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin, with its ability to modulate immune responses and inhibit JNK signaling, might induce CCDC134 expression by enhancing cellular pathways related to T cell activation and JNK signaling, areas where CCDC134 is active. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein, known to influence ERK signaling and apoptosis, could stimulate the expression of CCDC134 by modulating these cellular pathways where both ERK and CCDC134 are involved. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine, by altering gene expression as a DNA methyltransferase inhibitor, might increase CCDC134 production by influencing broader gene expression patterns. | ||||||