Date published: 2026-1-22

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Cbl-b Antibodies

Santa Cruz Biotechnology delivers a wide array of Cbl-b monoclonal antibodies for research focused on understanding cellular processes. Cbl-b Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Cbl-b, an E3 ubiquitin ligase, plays a critical role in regulating immune responses and maintaining T cell homeostasis. Through mediating ubiquitination and degradation of key signaling proteins, Cbl-b functions as an essential regulator of T cell activation and helps prevent autoimmunity. Understanding Cbl-b mechanisms has significant implications for developing new therapeutic strategies in immunology. Researchers can utilize Cbl-b monoclonal antibodies to investigate protein expression, localization, and interactions in various experimental settings. Current studies with Cbl-b monoclonal antibodies are expanding knowledge of immune system regulation and its impact on human health. Ongoing research with Cbl-b monoclonal antibodies continues to reveal new insights about immune cell signaling pathways. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of immune regulation and its therapeutic applications.

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Cbl-b Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Cbl-b Antibody (G-1)

sc-8006mouse IgG1 κ29-483 (h)WB, IP, IF, IHC(P), ELISAm, r, h
86
(17)

Cbl-b Antibody (B-5)

sc-376409mouse IgG2b κ953-982 (h)WB, IP, IF, IHC(P), ELISAm, r, h
7
(5)

Cbl-b CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Cbl-b CRISPR/Cas9 KO Plasmid (h)

sc-400828hGene KnockoutGFP0
(0)

Cbl-b HDR Plasmid (h)

sc-400828-HDRhHomology Directed RepairPuromycin0
(0)

Cbl-b Double Nickase Plasmid (h)

sc-400828-NIChGene KnockoutPuromycin0
(0)

Cbl-b Double Nickase Plasmid (h2)

sc-400828-NIC-2hGene KnockoutPuromycin0
(0)

Cbl-b CRISPR/Cas9 KO Plasmid (m)

sc-431578mGene KnockoutGFP0
(0)

Cbl-b HDR Plasmid (m)

sc-431578-HDRmHomology Directed RepairPuromycin0
(0)

Cbl-b CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Cbl-b CRISPR Activation Plasmid (h)

sc-400828-ACThGene ActivationPuro, Blast, Hygro0
(0)

Cbl-b siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Cbl-b siRNA (h)

sc-29950hGene SilencingN/A
9
(0)

Cbl-b shRNA Plasmid (h)

sc-29950-SHhGene SilencingPuromycin
9
(0)

Cbl-b shRNA (h) Lentiviral Particles

sc-29950-VhGene SilencingPuromycin
9
(0)

Cbl-b siRNA (m)

sc-29951mGene SilencingN/A0
(0)

Cbl-b shRNA Plasmid (m)

sc-29951-SHmGene SilencingPuromycin0
(0)

Cbl-b shRNA (m) Lentiviral Particles

sc-29951-VmGene SilencingPuromycin0
(0)

Cbl-b siRNA (r)

sc-63343rGene SilencingN/A0
(0)

Cbl-b shRNA Plasmid (r)

sc-63343-SHrGene SilencingPuromycin0
(0)

Cbl-b shRNA (r) Lentiviral Particles

sc-63343-VrGene SilencingPuromycin0
(0)