caspase-5 Activators
The chemical class caspase-5 Activators includes compounds that can indirectly influence the activity of caspase-5, primarily through modulation of the immune response and inflammasome activation. This class comprises a variety of compounds that stimulate innate immune responses, such as Lipopolysaccharides (LPS), ATP, and flagellin. These compounds can activate the inflammasome, a multiprotein complex involved in the immune response, which in turn can lead to the activation of caspase-5.
Additionally, substances like nigericin, aluminum hydroxide, and monosodium urate can induce inflammasome assembly and activation, thereby potentially stimulating caspase-5. Calcium ionophores, muramyl dipeptide, and synthetic compounds like imiquimod and Pam3CSK4, mimic the action of bacterial components or modify immune responses, potentially leading to the activation of caspase-5. Zymosan also contributes to this class by triggering immune responses through recognition as foreign entities, which may lead to inflammasome activation and subsequent caspase-5 activity.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Adenosine 5′-Triphosphate, disodium salt | 987-65-5 | sc-202040 sc-202040A | 1 g 5 g | $39.00 $75.00 | 9 | |
Serves as a danger signal in the immune system, potentially leading to inflammasome activation which can activate caspase-5. | ||||||
Nigericin sodium salt | 28643-80-3 | sc-201518A sc-201518 sc-201518B sc-201518C sc-201518D | 1 mg 5 mg 25 mg 1 g 5 g | $46.00 $112.00 $240.00 $7079.00 $27417.00 | 9 | |
Potassium ionophore that can trigger the inflammasome, potentially leading to caspase-5 activation. | ||||||
Aluminum hydroxide | 21645-51-2 | sc-214529 sc-214529A | 100 g 500 g | $39.00 $55.00 | 3 | |
Adjuvant that can stimulate the immune system, potentially leading to inflammasome activation and subsequent caspase-5 activity. | ||||||
Disodium citrate | 144-33-2 | sc-357341 sc-357341A | 25 g 100 g | $31.00 $71.00 | ||
Can form crystals that activate the inflammasome, potentially leading to caspase-5 activation. | ||||||
Imiquimod | 99011-02-6 | sc-200385 sc-200385A | 100 mg 500 mg | $67.00 $284.00 | 6 | |
Immune response modifier, can stimulate innate immunity potentially leading to caspase-5 activation. | ||||||
Zymosan | 9010-72-4 | sc-296863 sc-296863A | 100 mg 1 g | $99.00 $599.00 | 1 | |
Component of yeast cell walls, can trigger immune response potentially leading to caspase-5 activation. | ||||||