calsyntenin-2 Inhibitors
Calsyntenin-2 inhibitors comprise a diverse array of compounds targeting specific cellular pathways to modulate the expression and function of calsyntenin-2. Ionomycin, a calcium ionophore, elevates intracellular calcium levels, influencing calsyntenin-2 through calcium-dependent processes. Similarly, Thapsigargin, a sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) inhibitor, induces ER stress, perturbing cellular homeostasis and potentially impacting calsyntenin-2 function via stress-related pathways.
Wortmannin, a PI3-kinase inhibitor, disrupts the PI3K/Akt pathway, altering downstream cascades that indirectly influence calsyntenin-2 expression. Additionally, Bisindolylmaleimide I, a Protein Kinase C (PKC) inhibitor, modulates PKC-dependent pathways, impacting calsyntenin-2 dynamics indirectly through altered PKC-linked cascades. These inhibitors collectively demonstrate a mechanistic diversity, influencing calsyntenin-2 via various cellular pathways, providing valuable tools for probing its regulatory mechanisms in cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Calcium ionophore affecting intracellular calcium levels. Modulates downstream pathways, influencing calsyntenin-2 via calcium-dependent processes. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
PI3-kinase inhibitor disrupting the PI3K/Akt pathway. Alters cellular signaling cascades, potentially affecting calsyntenin-2 expression and function indirectly. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $103.00 $237.00 | 36 | |
Protein kinase C (PKC) inhibitor impacting PKC-dependent pathways. Modulation of PKC-linked cascades can indirectly influence calsyntenin-2 dynamics. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) inhibitor leading to ER stress. Perturbs cellular homeostasis, potentially affecting calsyntenin-2 function through stress-related pathways. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
p38 MAP kinase inhibitor influencing the MAPK pathway. Alters signaling events that can indirectly modulate calsyntenin-2 expression and activity. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor affecting the JNK pathway. Modulates cellular stress responses, potentially impacting calsyntenin-2 indirectly through stress-related cascades. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3-kinase inhibitor disrupting the PI3K/Akt pathway. Alters intracellular signaling cascades, potentially affecting calsyntenin-2 expression and dynamics. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor influencing the mTOR pathway. Modulation of mTOR-dependent processes can indirectly impact calsyntenin-2 expression and function. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
MEK inhibitor impacting the MAPK/ERK pathway. Alters downstream signaling cascades, potentially influencing calsyntenin-2 expression and dynamics. | ||||||
BAPTA/AM | 126150-97-8 | sc-202488 sc-202488A | 25 mg 100 mg | $138.00 $449.00 | 61 | |
Intracellular calcium chelator impacting calcium-dependent processes. Modulates downstream pathways, potentially influencing calsyntenin-2 via calcium-mediated signaling events. | ||||||