Items 71 to 80 of 167 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Nicotinic acid adenine dinucleotide phosphate sodium salt | 5502-96-5 | sc-215564 sc-215564A | 10 mg 25 mg | $472.00 $975.00 | ||
Nicotinic acid adenine dinucleotide phosphate sodium salt acts as a calcium channel modulator by influencing the phosphorylation state of calcium channels, thereby altering their gating mechanisms. Its unique ability to participate in redox reactions enhances its interaction with channel proteins, promoting conformational changes that affect calcium ion flow. This modulation can impact various intracellular signaling cascades, highlighting its role in regulating cellular excitability and calcium dynamics. | ||||||
Tetrahydropalmatine hydrochloride | 6024-85-7 | sc-296504 | 1 mg | $160.00 | ||
Tetrahydropalmatine hydrochloride functions as a calcium channel modulator by selectively binding to specific receptor sites on calcium channels, leading to altered ion permeability. Its unique structural features facilitate interactions with lipid bilayers, influencing channel conformation and kinetics. This compound exhibits distinct allosteric modulation, which can fine-tune the activation thresholds of calcium channels, thereby impacting cellular calcium homeostasis and signaling pathways. | ||||||
DHBP dibromide | 6159-05-3 | sc-203564 | 2 g | $83.00 | ||
DHBP dibromide acts as a calcium channel modulator through its ability to interact with the lipid environment surrounding calcium channels, promoting conformational changes that affect ion flow. Its unique dibromide substituents enhance hydrophobic interactions, influencing channel dynamics and gating mechanisms. The compound's reactivity as an acid halide allows for specific covalent modifications, potentially altering the kinetics of calcium influx and downstream signaling cascades. | ||||||
(+)-Egenine | 6883-44-9 | sc-203038 sc-203038A | 25 mg 100 mg | $140.00 $419.00 | ||
(+)-Egenine functions as a calcium channel modulator by selectively binding to specific sites on the channel proteins, inducing allosteric changes that regulate ion permeability. Its unique stereochemistry facilitates distinct interactions with membrane lipids, enhancing channel stability and influencing activation thresholds. The compound's ability to form transient complexes with calcium ions alters the kinetics of channel opening and closing, thereby modulating cellular excitability and signaling pathways. | ||||||
(±)-Methoxyverapamil Hydrochloride | 16662-47-8 | sc-202706 | 25 mg | $42.00 | ||
(±)-Methoxyverapamil Hydrochloride acts as a calcium channel modulator through its ability to interact with the voltage-gated calcium channels, stabilizing their inactive state. This compound exhibits unique hydrophobic interactions with the channel's lipid bilayer, which can influence the conformational dynamics of the protein. Its dual enantiomeric nature allows for varied binding affinities, potentially affecting the rate of calcium ion flux and altering cellular calcium homeostasis. | ||||||
Dantrolene, Sodium Salt Hemiheptahydrate | 24868-20-0 | sc-218075 | 100 mg | $115.00 | ||
Dantrolene, Sodium Salt Hemiheptahydrate functions as a calcium channel modulator by selectively inhibiting ryanodine receptors, which play a crucial role in calcium release from the sarcoplasmic reticulum. This compound exhibits unique binding characteristics, leading to altered calcium signaling pathways. Its distinct solubility profile enhances its interaction with cellular membranes, influencing the kinetics of calcium ion transport and modulating muscle contraction dynamics. | ||||||
Flunarizine • 2HCl | 30484-77-6 | sc-201473 sc-201473A sc-201473B | 1 g 10 g 50 g | $68.00 $400.00 $1683.00 | 1 | |
Flunarizine • 2HCl acts as a calcium channel modulator by blocking L-type calcium channels, thereby influencing intracellular calcium levels. Its unique ability to stabilize the channel in an inactive state alters calcium influx, impacting various cellular processes. The compound exhibits a high affinity for specific binding sites, which affects its kinetics and interaction with lipid membranes, ultimately modulating neuronal excitability and vascular tone. | ||||||
Diltiazem hydrochloride | 33286-22-5 | sc-200199 sc-200199A sc-200199B sc-200199C sc-200199D sc-200199E sc-200199F | 1 g 5 g 10 g 50 g 100 g 500 g 1 kg | $39.00 $153.00 $224.00 $510.00 $918.00 $2295.00 $4080.00 | 1 | |
Diltiazem hydrochloride functions as a calcium channel modulator by selectively inhibiting L-type calcium channels, leading to a reduction in calcium ion permeability across cell membranes. This compound demonstrates a unique binding affinity that stabilizes the channel in a closed conformation, effectively altering the dynamics of calcium influx. Its distinct interaction with membrane lipids influences cellular signaling pathways, contributing to the modulation of smooth muscle contraction and cardiac function. | ||||||
Loperamide Hydrochloride | 34552-83-5 | sc-203116 | 5 g | $75.00 | ||
Loperamide Hydrochloride acts as a calcium channel modulator by interacting with voltage-gated calcium channels, particularly affecting the influx of calcium ions in excitable tissues. Its unique structural features allow it to preferentially bind to specific channel conformations, thereby influencing the kinetics of calcium entry. This modulation can alter intracellular calcium levels, impacting various cellular processes and signaling cascades, while also affecting the overall excitability of neuronal and muscular tissues. | ||||||
Naphtho[1,2-d]thiazol-2-ylamine | 40172-65-4 | sc-279906 | 1 g | $245.00 | ||
Naphtho[1,2-d]thiazol-2-ylamine functions as a calcium channel modulator by selectively engaging with calcium channels, leading to altered gating dynamics. Its unique thiazole and naphthalene moieties facilitate specific interactions with channel proteins, enhancing or inhibiting calcium ion permeability. This compound's ability to stabilize certain channel states can significantly influence calcium-dependent signaling pathways, thereby modulating cellular excitability and function. | ||||||