CaBP1 Activators
Calcium-binding protein 1 (CaBP1) is a member of the neuronal calcium sensor (NCS) family, which is characterized by its ability to bind calcium and influence various cellular processes. CaBP1, also known as caldendrin, is closely related to calmodulin, a well-known calcium-binding protein, and shares structural similarities with it, including EF-hand motifs that facilitate calcium binding.
Expressed predominantly in the brain, CaBP1 plays a significant role in the central nervous system's function. It is involved in modulating calcium signaling pathways that are essential for neuronal activity, synaptic plasticity, and long-term potentiation, all of which are critical for learning and memory. CaBP1 interacts with a variety of target proteins, including ion channels like voltage-dependent calcium channels (VDCCs) and inositol 1,4,5-trisphosphate receptors (IP3Rs), thereby influencing their activity and the overall calcium dynamics within neurons.The precise mechanisms of CaBP1's action are complex and involve both the buffering of intracellular calcium levels and the regulation of calcium-dependent signaling cascades. Its expression and function are tightly regulated, ensuring that calcium signaling remains finely tuned to maintain neuronal health and blcok dysregulation that could lead to neurological disorders.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
It may enhance CaBP1 expression by modulating calcium metabolism and signaling pathways. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
It could influence CaBP1 expression through its role in gene regulation and cellular differentiation. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
It may upregulate CaBP1 by activating cAMP pathways, which can lead to changes in gene expression. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
It might affect CaBP1 expression through estrogen receptor-mediated signaling pathways. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
As a glucocorticoid, it may influence CaBP1 expression by affecting transcription factor activity. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
It may upregulate CaBP1 by modulating glycogen synthase kinase 3 (GSK-3) signaling pathways. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin can potentially increase CaBP1 expression by affecting glucose uptake and metabolism. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
cAMP may induce CaBP1 expression by activating protein kinase A (PKA) and modulating transcription factors. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
It may induce CaBP1 as part of the cellular response to oxidative stress. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
This calcium ionophore can increase intracellular calcium levels, potentially upregulating CaBP1 expression. | ||||||