C3orf14 Activators
Centrosomal protein 15 (CEP15) is a component of the centrosome, which is the primary microtubule-organizing center in eukaryotic cells. The centrosome plays a pivotal role in orchestrating cell division by helping to form the spindle apparatus that segregates chromosomes during mitosis. CEP15, as part of this complex structure, is presumed to contribute to the proper functioning and maintenance of the centrosome's integrity and dynamics.Although specific functions of CEP15 may not be fully elucidated, proteins like CEP15 are generally involved in critical cellular processes. These include the regulation of the cell cycle, ensuring accurate cell division, and playing a role in the checkpoint mechanisms that block cells from dividing with damaged DNA or misaligned chromosomes. Additionally, centrosomal proteins are often implicated in the spatial organization of the cell, influencing where certain organelles are positioned and how the cell responds to its environment.
Mutations or dysregulation of centrosomal proteins can lead to a variety of diseases, including cancer, due to their role in cell cycle control. The precise expression and localization of CEP15 are likely to be tightly regulated to maintain cellular homeostasis.Research into CEP15 and other centrosomal proteins continues to be an important area of cell biology, with implications for understanding the fundamental mechanisms of cell division and its errors that lead to disease.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid can influence cell differentiation and may affect the expression of proteins involved in cell cycle control. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This DNA methyltransferase inhibitor may cause demethylation of genes, leading to altered expression patterns. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium influences glycogen synthase kinase 3 (GSK-3) activity, which is involved in Wnt signaling, affecting cell cycle and centrosome functions. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
As an mTOR inhibitor, rapamycin can affect cell growth and proliferation, potentially impacting centrosome dynamics. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
This compound disrupts calcium homeostasis in cells, which can lead to stress responses that alter gene expression. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $92.00 $260.00 | 42 | |
As a cyclin-dependent kinase inhibitor, it can halt cell cycle progression, which may influence centrosome protein expression. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
By stabilizing microtubules, it affects cell division and may impact the expression of centrosomal proteins. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
This histone deacetylase inhibitor can lead to hyperacetylation of histones, affecting gene expression. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
It inhibits ribonucleotide reductase, affecting DNA synthesis and potentially altering the expression of cell cycle-related proteins. | ||||||