C22orf43 Inhibitors

"ASPR1," is a protein whose name suggests the presence of an aspartate-rich (Asp-rich) domain. While the exact functions and characteristics of ASPR1 may not be well-documented or entirely understood, we can infer possible roles based on the common features of aspartate-rich motifs in proteins.Aspartate-rich motifs are known to participate in the catalytic functions of several types of enzymes, such as those involved in the non-oxidative phase of the pentose phosphate pathway and the biosynthesis of amino acids and nucleotides. The aspartate residues typically contribute to the binding of substrates or cofactors, and they may be involved in the catalytic mechanism itself, often by stabilizing charged intermediates during enzymatic reactions.

Given its name, ASPR1 might function as an enzyme or a binding protein where the aspartate-rich region plays a crucial role in the interaction with other molecules. This could allow ASPR1 to be involved in a variety of metabolic or signaling pathways, depending on its specific structure and the cellular context.In proteins where aspartate-rich domains are found, they often chelate metal ions that are necessary for enzymatic activity or facilitate the formation of protein complexes. Therefore, ASPR1 might also have a role in metal ion homeostasis or signaling pathways that are regulated by metal ion-dependent conformational changes.