C20orf46 Activators

Transmembrane Protein 74B, often abbreviated as TMEM74B, is a protein that in humans is encoded by the TMEM74B gene. As the name suggests, TMEM74B is a transmembrane protein, which means it spans across the lipid bilayer of cells and is involved in a variety of cellular processes due to its location within the membrane. Transmembrane proteins like TMEM74B are integral to the membrane and play key roles in cell signaling, transport, and maintaining the structural integrity of cells.The specific functions of TMEM74B are not fully characterized, but transmembrane proteins, in general, are known to participate in the relay of signals from the external environment to the cell's interior, acting as gateways or conduits for molecules to pass in and out of the cell. They can also serve as receptors for ligands, initiating intracellular signaling cascades upon ligand binding which result in cellular responses to external stimuli.

TMEM74B's structure suggests that it may be involved in these types of activities, potentially interacting with other proteins or small molecules within the cell membrane or the extracellular matrix. Its role could be significant in processes such as cell adhesion, cellular communication, or the regulation of ion channels and transporters that are essential for maintaining homeostasis within cells.As with many transmembrane proteins, TMEM74B may also be implicated in human health and disease. Anomalies in transmembrane protein function can lead to a wide range of diseases, including cancer, neurodegenerative disorders, and metabolic syndromes.