Key pathways that could be relevant to C20orf173's function include the PI3K/Akt/mTOR pathway, the MAPK/ERK pathway, and the ubiquitin-proteasome system. Rapamycin and LY294002, by inhibiting mTOR and PI3K respectively, can affect cell growth and survival pathways. U0126 and PD98059, targeting MEK in the MAPK/ERK pathway, are involved in cell differentiation and proliferation, potentially intersecting with C20orf173-related processes.
Inhibitors like Bortezomib and MG132 target the proteasome, affecting protein turnover and degradation, which can influence a range of cellular signaling pathways. DAPT, as a γ-secretase inhibitor, affects Notch signaling, a pathway significant in cell fate decisions and differentiation.These inhibitors represent a broad spectrum of cellular targets and processes, offering potential indirect means to influence the activity of C20orf173
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