Compounds such as Wortmannin and LY294002 exert their effect by inhibiting PI3K, thereby attenuating Akt signaling, which can have downstream effects on proteins like C16orf55 that are regulated by this pathway. Similarly, molecules like Triciribine and Rapamycin exert their action through the Akt/mTOR pathway, which is known to regulate a multitude of cellular functions, including those associated with proteins like C16orf55.
Additionally, cell cycle inhibitors like Palbociclib and Roscovitine may impact C16orf55 by altering the cell cycle environment, which in turn could affect the stability and activity of this protein. Inhibition of signaling molecules such as JNK by SP600125, p38 MAPK by SB203580, and MEK by U0126 can lead to alterations in the cellular stress response, influencing the network in which C16orf55 operates. Compounds such as Dasatinib, which targets Src kinases, can also modify the activity of various signaling pathways that intersect with the biological processes involving C16orf55. Thapsigargin and Cyclopamine, by inducing ER stress and inhibiting the Hedgehog pathway respectively, can lead to changes in cellular homeostasis, which may affect the function or level of C16orf55 within the cell.
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