β-defensin 3 Activators
β-defensin 3 activators belong to a class of molecules that play a significant role in the innate immune system's defense against microbial infections. β-defensin 3, also known as human beta-defensin 3 (hBD-3), is a small cationic peptide that is produced by various epithelial cells in the body, including those in the skin, respiratory tract, and gastrointestinal tract. These peptides are an essential part of the body's first line of defense against pathogens, such as bacteria, fungi, and viruses.
β-defensin 3 activators are substances or mechanisms that enhance the expression or activity of β-defensin 3 within cells. These activators may work by stimulating the transcription of the gene encoding β-defensin 3 or by promoting its secretion and antimicrobial function. Once produced and secreted, β-defensin 3 acts as a potent antimicrobial peptide by disrupting the integrity of microbial cell membranes, leading to cell death. This serves as a crucial mechanism to help protect the host from infection by a wide range of pathogens. Additionally, β-defensin 3 is involved in modulating the inflammatory response, chemotaxis of immune cells, and wound healing processes. In summary, β-defensin 3 activators play a vital role in the body's innate immune response by promoting the production and function of β-defensin 3, which serves as a key component in the defense against microbial invaders and contributes to overall immune defense mechanisms.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $220.00 $645.00 $1000.00 $1500.00 $440.00 | 32 | |
This active form of vitamin D can modulate immune responses and may enhance the expression of β-defensin 3 in epithelial cells. | ||||||
Polyinosinic-polycytidylic acid potassium salt | 31852-29-6 | sc-202767 | 5 mg | $198.00 | ||
This synthetic analog of double-stranded RNA mimics viral infection, possibly inducing β-defensin 3 as part of the antiviral response. | ||||||
Imiquimod | 99011-02-6 | sc-200385 sc-200385A | 100 mg 500 mg | $67.00 $284.00 | 6 | |
Recognized as an immune response modifier, imiquimod may induce β-defensin 3 expression through toll-like receptor pathways. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
This plant-derived compound, known for its antioxidant properties, may also modulate immune functions, potentially inducing β-defensin 3. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A component of turmeric, curcumin may influence various signaling pathways involved in immune response, possibly upregulating β-defensin 3. | ||||||
Butyric acid | 107-92-6 | sc-214640 sc-214640A | 1 kg 10 kg | $64.00 $177.00 | ||
A short-chain fatty acid, Butyric acid is known for its role in gut health and may enhance β-defensin 3 expression in intestinal epithelial cells. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Found in cruciferous vegetables, sulforaphane is studied for its role in cellular defense mechanisms, which may include inducing β-defensin 3 expression. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
An essential mineral, zinc plays a critical role in immune function and may be involved in the upregulation of β-defensin 3 in response to immune challenges. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
A metabolite of vitamin A, retinoic acid is involved in immune regulation and may enhance the expression of β-defensin 3 in certain cells. | ||||||