Bag-3 Activators
Bag-3 activators constitute a diverse group of chemicals that modulate the Bag-3 protein through various signaling pathways and cellular processes. AICAR and A769662, as AMPK activators, regulate cellular energy homeostasis, impacting Bag-3 stability and function in processes sensitive to energy availability. Resveratrol and Honokiol, activating SIRT1 and SIRT3, respectively, influence Bag-3 through deacetylation of key regulatory proteins, modulating its role in cellular homeostasis and stress responses. Betulinic Acid and Enoxacin activate p53, indirectly influencing Bag-3 expression and function in cellular processes associated with stress responses and apoptosis. Metformin, Trehalose, and Forskolin, as AMPK and cAMP activators, modulate Bag-3 by regulating cellular energy homeostasis and signaling pathways responsive to cAMP, impacting Bag-3 function in processes sensitive to these pathways.
SB216763, a GSK-3 activator, modulates the Wnt signaling pathway, indirectly influencing Bag-3 by altering the regulatory dynamics of the pathway. PPAR-γ activators, including Thiazolidinediones, regulate gene expression, modulating the cellular environment and impacting Bag-3 function in processes related to inflammation and cellular stress responses. Uridine Triphosphate (UTP), activating P2Y receptors, influences Bag-3 by modulating cellular signaling pathways, impacting its role in processes regulated by purinergic receptors, such as cellular stress responses. Collectively, these Bag-3 activators offer valuable tools for dissecting the intricate regulatory networks governing Bag-3 in cellular processes.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR, an AMP-activated protein kinase (AMPK) activator, influences cellular energy metabolism. Activated AMPK modulates Bag-3 through energy-sensitive pathways, regulating its participation in cellular processes dependent on energy status. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, a polyphenol, activates SIRT1, a NAD+-dependent deacetylase. SIRT1, when activated, influences Bag-3 by deacetylating key regulatory proteins, impacting its function within cellular processes and maintaining cellular homeostasis. | ||||||
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $115.00 $337.00 | 3 | |
Betulinic Acid activates p53, a transcription factor involved in various cellular processes. Activated p53 influences Bag-3 expression and function, contributing to the modulation of cellular pathways associated with stress responses and apoptosis. | ||||||
A-769662 | 844499-71-4 | sc-203790 sc-203790A sc-203790B sc-203790C sc-203790D | 10 mg 50 mg 100 mg 500 mg 1 g | $180.00 $726.00 $1055.00 $3350.00 $5200.00 | 23 | |
A769662, an AMPK activator, impacts Bag-3 by regulating cellular energy homeostasis. Activated AMPK influences Bag-3 stability and function, particularly in contexts where cellular energy availability is a crucial determinant of cellular processes. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Metformin, an AMPK activator, modulates cellular energy metabolism. AMPK activation by Metformin indirectly influences Bag-3, as the protein is interconnected with energy-sensitive pathways, and its function is sensitive to cellular energy status. | ||||||
Enoxacin | 74011-58-8 | sc-205670 sc-205670A | 500 mg 1 g | $39.00 $48.00 | 2 | |
Enoxacin, a fluoroquinolone antibiotic, activates AMPK. This activation influences Bag-3 by modulating cellular energy metabolism, impacting its role in stress responses and cellular processes that are sensitive to changes in energy availability. | ||||||
Honokiol | 35354-74-6 | sc-202653 sc-202653A | 10 mg 25 mg | $118.00 $178.00 | 4 | |
Honokiol activates SIRT3, a mitochondrial deacetylase. SIRT3 activation indirectly influences Bag-3 by deacetylating mitochondrial proteins, altering the cellular environment in which Bag-3 operates and impacting its participation in cellular processes. | ||||||
D-(+)-Trehalose Anhydrous | 99-20-7 | sc-294151 sc-294151A sc-294151B | 1 g 25 g 100 g | $29.00 $164.00 $255.00 | 2 | |
Trehalose, a disaccharide, activates AMPK and enhances autophagy. AMPK activation influences Bag-3 by regulating cellular energy homeostasis, while enhanced autophagy modulates Bag-3 turnover and function within cellular processes responsive to autophagic activity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels. Elevated cAMP levels indirectly influence Bag-3 by modulating cellular signaling pathways responsive to cAMP, impacting Bag-3 function in processes regulated by these signaling cascades. | ||||||
Uridine-5′-triphosphate, Trisodium Salt | 19817-92-6 | sc-301964 sc-301964A | 50 mg 1 g | $86.00 $118.00 | 2 | |
UTP, a nucleotide, activates P2Y receptors. Activation of P2Y receptors indirectly influences Bag-3 by modulating cellular signaling pathways, impacting Bag-3 function in processes regulated by these purinergic receptors, such as cellular stress responses. | ||||||