Date published: 2026-4-1

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Amylase 2A Inhibitors

Common Amylase 2A Inhibitors include, but are not limited to Acarbose CAS 56180-94-0, Miglitol CAS 72432-03-2, Voglibose CAS 83480-29-9, Pramlintide-d3 CAS 151126-32-8 and Nateglinide CAS 105816-04-4.

Amylase 2A inhibitors belong to a specific chemical class of compounds that have been meticulously designed to modulate the activity of alpha-amylase 2A, an enzyme crucially involved in carbohydrate metabolism. Alpha-amylase 2A plays a significant role in breaking down complex carbohydrates into simpler sugars, facilitating their absorption and utilization by the body. These inhibitors are thoughtfully crafted molecules engineered to interact with alpha-amylase 2A, influencing its normal function. Through these interactions, they might impact various cellular processes associated with carbohydrate digestion and metabolism, without directly altering its catalytic sites or its involvement in carbohydrate breakdown.

The design of alpha-amylase 2A inhibitors is grounded in a comprehensive understanding of the structural and functional attributes of the enzyme. Typically developed using advanced chemical synthesis methods and informed by insights from enzymology and metabolic pathways, these inhibitors are characterized by their ability to selectively bind to alpha-amylase 2A. This selectivity enables focused modulation of cellular pathways that rely on the activity of this specific enzyme. The development and utilization of alpha-amylase 2A inhibitors contribute to advancing our understanding of the complex interplay between enzymatic processes and metabolic dynamics, offering insights into the fundamental molecular mechanisms that govern carbohydrate digestion, absorption, and energy utilization in various organisms.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Acarbose

56180-94-0sc-203492
sc-203492A
1 g
5 g
$226.00
$605.00
1
(1)

Delays carbohydrate digestion by competitively inhibiting amylase, reducing postprandial glucose levels.

Miglitol

72432-03-2sc-221943
10 mg
$161.00
1
(1)

Slows carbohydrate breakdown by competitively inhibiting amylase, leading to reduced glucose absorption.

Voglibose

83480-29-9sc-204384
sc-204384A
10 mg
50 mg
$198.00
$681.00
(1)

Inhibits amylase to delay carbohydrate digestion, controlling post-meal blood glucose levels.

BAY-876

1799753-84-6sc-507539
5 mg
$240.00
(0)

Inhibits pancreatic α-amylase, potentially useful in glycemic control.

Pramlintide-d3

151126-32-8 (free base)sc-476347
0.25 mg
$490.00
(0)

Inhibits postprandial glucagon secretion, potentially impacting carbohydrate metabolism.

Nateglinide

105816-04-4sc-394067
sc-394067A
10 mg
25 mg
$192.00
$265.00
(0)

Stimulates insulin secretion and inhibits amylase, promoting post-meal glucose control.

Sitagliptin

486460-32-6sc-482298
sc-482298A
sc-482298B
25 mg
100 mg
1 g
$213.00
$473.00
$733.00
10
(0)

Enhances incretin hormones, potentially influencing postprandial carbohydrate metabolism.

Vildagliptin

274901-16-5sc-208485
10 mg
$176.00
4
(1)

Inhibits DPP-4 enzyme to extend the activity of incretin hormones, impacting glucose homeostasis.