Date published: 2025-9-5

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AMPK Activators

Santa Cruz Biotechnology now offers a broad range of AMPK Activators for use in various applications. AMPK (AMP-activated protein kinase) activators are a crucial category of chemicals in scientific research, especially in the study of cellular energy homeostasis and metabolic regulation. AMPK is a key regulatory enzyme that monitors cellular energy status and is activated in response to low energy levels, playing a significant role in maintaining energy balance within cells. The use of AMPK activators allows researchers to investigate the mechanisms by which cells sense and respond to changes in energy availability, as well as to explore the pathways involved in metabolic processes such as glucose uptake, fatty acid oxidation, and mitochondrial biogenesis. These activators are instrumental in dissecting the role of AMPK in various physiological contexts, including stress responses, exercise physiology, and nutrient sensing. By modulating AMPK activity, scientists can study its impact on metabolic pathways, providing insights into how cells adapt to energetic stress and maintain homeostasis. Additionally, AMPK activators are valuable tools in molecular biology and biochemistry for probing the regulatory networks that control cellular metabolism and for identifying potential targets for metabolic engineering. The ability to precisely control AMPK activity with these activators enhances our understanding of the enzyme's function and its broader implications in metabolic regulation. The application of AMPK activators extends to research in bioenergetics, where they are used to study energy metabolism in various cell types and organisms, contributing to the advancement of knowledge in cellular physiology and metabolic biology. View detailed information on our available AMPK Activators by clicking on the product name.

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Items 11 to 16 of 16 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Cryptotanshinone

35825-57-1sc-280649
10 mg
$117.00
1
(1)

Cryptotanshinone is a potent activator of AMPK, exhibiting unique interactions that enhance the enzyme's catalytic efficiency. Its structure allows for specific binding to regulatory sites, which stabilizes the active conformation of AMPK. This compound influences the phosphorylation dynamics of key substrates, modulating energy-sensing pathways. Additionally, Cryptotanshinone's ability to alter cellular redox states contributes to its role in metabolic signaling, impacting overall energy balance.

Rosiglitazone Maleate

155141-29-0sc-280069
20 mg
$163.00
1
(1)

Rosiglitazone Maleate functions as an AMPK modulator, engaging in distinctive molecular interactions that promote the enzyme's activation. Its unique structural features facilitate binding to allosteric sites, enhancing AMPK's stability and activity. This compound influences metabolic pathways by altering the phosphorylation of target proteins, thereby affecting energy homeostasis. Furthermore, Rosiglitazone Maleate's impact on lipid metabolism and glucose uptake underscores its role in cellular energy regulation.

AMPK Activator

849727-81-7sc-203819A
sc-203819
sc-203819B
sc-203819C
sc-203819D
1 mg
5 mg
10 mg
50 mg
100 mg
$130.00
$225.00
$300.00
$900.00
$1700.00
1
(1)

AMPK Activator is a potent compound that enhances AMPK activity through specific interactions with its regulatory subunits. By stabilizing the enzyme's conformation, it promotes the phosphorylation of key metabolic targets, leading to increased energy expenditure. This activator uniquely influences cellular signaling pathways, modulating the balance between catabolic and anabolic processes. Its kinetic profile suggests rapid engagement with AMPK, facilitating swift metabolic adaptations in response to energy demands.

Compound 112254

949745-75-9sc-396660
sc-396660A
10 mg
50 mg
$105.00
$410.00
(0)

Compound 112254 is a selective AMPK modulator that engages with the enzyme's allosteric sites, promoting a conformational shift that enhances its catalytic efficiency. This compound uniquely influences the AMP/ATP ratio, driving metabolic reprogramming. Its interaction with downstream targets leads to a distinct activation of lipid oxidation pathways, while also impacting glucose uptake mechanisms. The compound exhibits a favorable kinetic profile, allowing for efficient modulation of energy homeostasis in cellular environments.

2-(4-Benzoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide

924416-43-3sc-396658
sc-396658A
10 mg
50 mg
$112.00
$454.00
1
(0)

2-(4-Benzoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide acts as a potent AMPK activator, facilitating the enzyme's phosphorylation processes through specific binding interactions. This compound uniquely stabilizes the enzyme's active conformation, enhancing its affinity for AMP. Its influence on metabolic signaling cascades promotes a shift in cellular energy dynamics, particularly affecting fatty acid metabolism and glucose homeostasis. The compound's structural features contribute to its selective engagement with AMPK, optimizing its regulatory effects on energy balance.

Adenosine phosphate(Vitamin B8)

61-19-8sc-278678
sc-278678A
50 g
100 g
$160.00
$240.00
(0)

Adenosine phosphate, known as Vitamin B8, plays a crucial role in cellular energy regulation by activating AMPK through unique allosteric interactions. This compound enhances the enzyme's catalytic efficiency, promoting its phosphorylation activity. By modulating key metabolic pathways, it influences ATP production and glucose uptake. Its structural characteristics allow for specific binding to AMPK, facilitating a dynamic response to cellular energy status and optimizing metabolic homeostasis.