ALDH1A1 Activators

Common ALDH1A1 Activators include, but are not limited to Retinoic Acid, all trans CAS 302-79-4, Disulfiram CAS 97-77-8, Resveratrol CAS 501-36-0, D,L-Sulforaphane CAS 4478-93-7 and Omeprazole CAS 73590-58-6.

ALDH1A1 (Aldehyde Dehydrogenase 1 Family Member A1) activators are compounds or molecules that enhance the activity or function of the ALDH1A1 enzyme. ALDH1A1 is a member of the aldehyde dehydrogenase enzyme family, which plays a crucial role in the oxidation of aldehydes, converting them into less reactive carboxylic acids. ALDH1A1, in particular, is primarily involved in the oxidation of retinaldehyde to form retinoic acid, a biologically active form of vitamin A. This enzymatic reaction is a key step in the biosynthesis of retinoic acid, which, in turn, serves as a critical regulator of various cellular processes, including cell growth, differentiation, and gene expression. ALDH1A1 activators are of great interest in the field of cell biology and pharmacology as they have the potential to modulate retinoic acid production and its downstream effects on cellular physiology.

Research on ALDH1A1 activators aims to understand how these compounds interact with the ALDH1A1 enzyme and how they influence its enzymatic activity. By enhancing ALDH1A1 activity, these activators can increase the production of retinoic acid within cells, leading to alterations in cellular processes controlled by retinoic acid signaling. This can have broad implications for the fields of development, regeneration, and disease, as retinoic acid is a critical signaling molecule involved in embryonic development, tissue regeneration, and the regulation of various genes. However, it's important to note that while research in this area is promising, the development of ALDH1A1 activators for specific applications is an ongoing area of study and may require further exploration.