AK129341 Inhibitors
AK129341 inhibitors represent a class of chemical compounds designed to target and modulate the activity of the protein encoded by the gene symbol AK129341, which may play a role in various intracellular pathways. This gene is believed to be associated with specific enzymatic or receptor functions within cellular environments, influencing signal transduction and metabolic regulation. The inhibition mechanism is often characterized by the binding of these chemical agents to the active site or allosteric sites of the protein product, thereby altering its conformational structure or functionality. This action reduces or completely halts the protein's ability to interact with other cellular components, affecting downstream molecular pathways that are normally influenced by its activity. This form of inhibition can be achieved through competitive, non-competitive, or irreversible binding, depending on the structural characteristics of the inhibitor and the target protein.
The structural diversity of AK129341 inhibitors allows for varied mechanisms of inhibition. Small molecules in this class often feature heterocyclic cores, aromatic substituents, or other moieties that enable precise interactions with the target protein. These inhibitors may exploit hydrogen bonding, van der Waals forces, or hydrophobic interactions to maintain specificity and affinity toward the AK129341 protein. In some cases, these compounds are designed to stabilize the inactive form of the target, preventing its transition into an active state. Additionally, the physicochemical properties of these inhibitors, such as solubility, molecular weight, and lipophilicity, are carefully tuned to optimize their activity within biological systems. The ability to modulate the AK129341 pathway through inhibition offers a tool for further understanding the complex biological functions associated with this protein.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole disrupts microtubule polymerization, which can inhibit centrosomal protein 126's function in microtubule nucleation and stabilization since the protein is implicated in microtubule organization at the centrosome. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Paclitaxel stabilizes microtubules and prevents their disassembly, which inhibits centrosomal protein 126's role in microtubule dynamics, an essential process for normal centrosomal function. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $100.00 $230.00 $450.00 $1715.00 $2900.00 | 4 | |
Vinblastine binds to tubulin and inhibits microtubule formation, which can inhibit centrosomal protein 126's function since it is associated with microtubule organization and stability at the centrosome. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Colchicine binds to tubulin, inhibiting its polymerization and thus microtubule assembly. This inhibition can affect centrosomal protein 126's function, as it is involved in the centrosomal anchoring of microtubules. | ||||||
Griseofulvin | 126-07-8 | sc-202171A sc-202171 sc-202171B | 5 mg 25 mg 100 mg | $83.00 $216.00 $586.00 | 4 | |
Griseofulvin disrupts microtubule function by binding to tubulin and can inhibit centrosomal protein 126's ability to participate in the formation and function of the mitotic spindle, which is essential for centrosome activity. | ||||||
Podophyllotoxin | 518-28-5 | sc-204853 | 100 mg | $82.00 | 1 | |
Podophyllotoxin inhibits tubulin polymerization, which can impede centrosomal protein 126's role in spindle assembly and centrosome integrity, as the protein is known to interact with microtubules at the centrosome. | ||||||
Eribulin | 253128-41-5 | sc-507547 | 5 mg | $865.00 | ||
Eribulin inhibits the growth phase of microtubules without affecting the shortening phase, which can inhibit centrosomal protein 126's involvement in microtubule dynamics and centrosome function. | ||||||
S-Trityl-L-cysteine | 2799-07-7 | sc-202799 sc-202799A | 1 g 5 g | $31.00 $65.00 | 6 | |
S-Trityl-L-cysteine is a specific inhibitor of Eg5 kinesin motor protein, which can inhibit centrosomal protein 126's role in centrosome separation and proper spindle assembly, as Eg5 is critical for these processes. | ||||||
Thiabendazole | 148-79-8 | sc-204913 sc-204913A sc-204913B sc-204913C sc-204913D | 10 g 100 g 250 g 500 g 1 kg | $31.00 $82.00 $179.00 $306.00 $561.00 | 5 | |
Thiabendazole disrupts microtubule assembly, which can inhibit centrosomal protein 126's function in microtubule-dependent processes at the centrosome, including spindle formation and centrosome duplication. | ||||||
Albendazole | 54965-21-8 | sc-210771 | 100 mg | $209.00 | 1 | |
Albendazole targets tubulin and inhibits its polymerization, leading to an inhibition of centrosomal protein 126's function related to microtubule elongation and spindle formation, which are crucial for centrosomal activities. | ||||||