AGS3 Activators
AGS3 activators comprise a diverse range of chemicals that can indirectly influence the activity of AGS3/GPSM1, a modulator of G-protein signaling. These activators do not directly interact with AGS3; instead, they affect the cellular signaling pathways in which AGS3 is involved, particularly the G-protein-mediated signaling pathways. The indirect activation of AGS3 by these compounds reflects the complexity of G-protein signaling regulation and the role of AGS3 in these processes.
Key to this regulation is the modulation of cAMP levels and G-protein-coupled receptor (GPCR) signaling. Compounds like Forskolin, Isoproterenol, Prostaglandin E2, Caffeine, Dopamine, Histamine, Adenosine, Nicotine, Serotonin, Epinephrine, Glutamate, and Acetylcholine interact with various GPCRs or influence cAMP levels, thereby indirectly affecting AGS3 activity. For instance, Forskolin, by activating adenylate cyclase, elevates cAMP levels, which can alter the dynamics of G-protein subunit interactions, potentially influencing AGS3's role in modulating G-protein signaling. Similarly, neurotransmitters and hormones such as Dopamine, Epinephrine, and Serotonin, through their action on respective GPCRs, contribute to the modulation of G-protein signaling pathways, potentially impacting AGS3 activity.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels. Elevated cAMP can modulate G-protein signaling, potentially influencing AGS3 activity indirectly by altering the balance of G-protein subunit interactions. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol, a beta-adrenergic agonist, can increase cAMP levels via G-protein-coupled receptor (GPCR) activation, indirectly affecting AGS3 by altering G-protein signaling dynamics. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
Prostaglandin E2 activates GPCRs, leading to changes in cAMP levels. This can indirectly affect AGS3 activity by modulating G-protein signaling pathways. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine inhibits phosphodiesterases, leading to increased cAMP levels. Elevated cAMP can alter G-protein signaling, potentially influencing AGS3 activity indirectly. | ||||||
Dopamine | 51-61-6 | sc-507336 | 1 g | $290.00 | ||
Dopamine, through its action on dopamine receptors (a type of GPCR), can modulate G-protein signaling, potentially affecting AGS3 activity. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $94.00 $283.00 $988.00 | 7 | |
Histamine, acting on GPCRs, can influence G-protein signaling pathways, potentially affecting AGS3 activity indirectly. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $34.00 $48.00 $300.00 $572.00 $1040.00 $2601.00 $4682.00 | 1 | |
Adenosine, through adenosine receptors (GPCRs), can modulate G-protein signaling, indirectly affecting AGS3. | ||||||
3-(2-Aminoethyl)-1H-indol-5-ol | 50-67-9 | sc-298707 | 1 g | $530.00 | 3 | |
Serotonin, via serotonin receptors (GPCRs), can influence G-protein signaling, indirectly affecting AGS3. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine, acting on adrenergic receptors (GPCRs), can modulate G-protein signaling, potentially affecting AGS3 activity. | ||||||
L-Glutamic Acid | 56-86-0 | sc-394004 sc-394004A | 10 g 100 g | $297.00 $577.00 | ||
Glutamate, through its action on metabotropic glutamate receptors (GPCRs), can influence G-protein signaling, potentially affecting AGS3 activity. | ||||||