ADAT2 Activators
ADAT2 Activators are a unique class of chemicals that enhance the functional activity of ADAT2, a protein implicated in tRNA adenosine deamination. Elevating levels of these chemicals can enhance ADAT2's activity either indirectly, by enhancing related metabolic processes, or directly, by enhancing the substrate availability for ADAT2. For instance, adenosine and inosine directly influence ADAT2 by enhancing the availability of its substrate and product, respectively. SAH and SAM, key components of the methylation cycle, can indirectly enhance ADAT2's activity by influencing the methylation status of tRNA, a process that ADAT2 is directly involved in.
Methionine, 5-MTHF, cobalamin, betaine, choline, trimethylglycine, folic acid, and DHF indirectly enhance ADAT2's activity by enhancing methylation processes. These chemicals are involved at various stages of the methylation cycle, either as precursors, products, or cofactors. Their increased levels can enhance methylation processes, promoting tRNA methylation, which can be influenced by ADAT2. By enhancing these related metabolic processes, these chemicals indirectly enhance the functional activity of ADAT2.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Homocysteine | 6027-13-0 | sc-507315 | 250 mg | $195.00 | ||
SAH, a product in the methylation cycle, can enhance ADAT2 activity. ADAT2 is involved in tRNA adenosine deamination, and its activity can be influenced by methylation status. Increased levels of SAH may promote ADAT2's adenosine deamination activity. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $33.00 $47.00 $294.00 $561.00 $1020.00 $2550.00 $4590.00 | 1 | |
Adenosine is a purine nucleoside that can be converted to inosine by ADAT2. Elevated adenosine levels can enhance the substrate availability for ADAT2, thus enhancing its adenosine deamination activity. | ||||||
L-Methionine | 63-68-3 | sc-394076 sc-394076A sc-394076B sc-394076C sc-394076D sc-394076E | 25 g 100 g 250 g 1 kg 5 kg 10 kg | $33.00 $36.00 $56.00 $148.00 $566.00 $1081.00 | ||
Methionine is a critical amino acid in the methylation cycle. Increased methionine can enhance the generation of SAM (S-adenosylmethionine), which is used in the methylation of tRNA, a process that can be influenced by ADAT2. | ||||||
Vitamin B12 | 68-19-9 | sc-296695 sc-296695A sc-296695B sc-296695C sc-296695D sc-296695E | 100 mg 1 g 5 g 25 g 100 g 1 kg | $39.00 $55.00 $204.00 $877.00 $3414.00 $9180.00 | 2 | |
Cobalamin is a necessary cofactor for methionine synthase, an enzyme involved in the methylation cycle. Increased cobalamin can enhance methylation processes, indirectly enhancing ADAT2's activity. | ||||||
Betaine | 107-43-7 | sc-214595 sc-214595A sc-214595B sc-214595C sc-214595D sc-214595E | 50 g 100 g 250 g 1 kg 2.5 kg 5 kg | $30.00 $40.00 $55.00 $160.00 $330.00 $580.00 | 2 | |
Betaine serves as a methyl donor in the conversion of homocysteine to methionine. Elevated betaine levels can enhance methylation processes, indirectly enhancing ADAT2 activity. | ||||||
Choline chloride | 67-48-1 | sc-207430 sc-207430A sc-207430B | 10 mg 5 g 50 g | $32.00 $36.00 $51.00 | 1 | |
Choline can be oxidized to betaine, which serves as a methyl donor in the methylation cycle. Increased choline can enhance methylation processes, indirectly enhancing ADAT2's activity. | ||||||
Inosine | 58-63-9 | sc-295182 sc-295182A | 1 g 5 g | $59.00 $90.00 | ||
Inosine is the product of adenosine deamination by ADAT2. Increased availability of inosine may indirectly enhance ADAT2's activity by facilitating the reaction equilibrium towards the substrate side. | ||||||
Folic Acid | 59-30-3 | sc-204758 | 10 g | $72.00 | 2 | |
Folic acid is a precursor of 5-MTHF, which is involved in the methylation cycle. Increased folic acid can enhance methylation processes, indirectly enhancing ADAT2 activity. | ||||||
Ademetionine | 29908-03-0 | sc-278677 sc-278677A | 100 mg 1 g | $180.00 $655.00 | 2 | |
SAM is a universal methyl donor, including in tRNA methylation. Increased SAM levels can enhance methylation processes, indirectly enhancing ADAT2's activity in adenosine deamination. | ||||||