Date published: 2025-9-28

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Acid Halides

Santa Cruz Biotechnology now offers a broad range of Acid Halides for use in various applications. Acid halides, also known as acyl halides, are a class of organic compounds derived from carboxylic acids by replacing the hydroxyl group (-OH) with a halide group (such as chloride, bromide, or fluoride). These compounds are highly reactive intermediates in organic synthesis due to the electrophilic nature of the carbonyl carbon, which readily undergoes nucleophilic acyl substitution reactions. Acid halides are pivotal in the synthesis of a wide array of chemical compounds, including esters, amides, and anhydrides, making them indispensable in chemical research and industrial processes. In scientific research, acid halides are frequently used to study reaction mechanisms and to develop new synthetic methodologies. Their reactivity also allows for the modification of complex molecules, facilitating the construction of elaborate molecular architectures and the introduction of functional groups that can be further manipulated. Additionally, acid halides play a crucial role in polymer chemistry, where they are used to produce polymers with specific structural and functional properties. Researchers have employed acid halides to explore the synthesis of novel materials, catalysts, and ligands, thereby advancing the fields of materials science, catalysis, and coordination chemistry. The availability of a wide variety of acid halides from Santa Cruz Biotechnology enables researchers to select the appropriate compound for their specific needs, thus driving innovation and discovery in multiple scientific disciplines. View detailed information on our available acid halides by clicking on the product name.

Items 1 to 10 of 374 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Hydrocinnamoyl chloride

645-45-4sc-250129
5 g
$25.00
(0)

Hydrocinnamoyl chloride is a chemical compound that functions as an acid halide. When used in this capacity, it reacts with various compounds to form esters, amides, and other derivatives. This reaction involves the substitution of the chlorine atom in the hydrocinnamoyl chloride molecule with another functional group, resulting in the formation of a new compound with different chemical properties. This process is commonly used in organic synthesis to create a wide range of chemical products.

2,3-Dichlorobenzoyl chloride

2905-60-4sc-265962
5 g
$77.00
(0)

2,3-Dichlorobenzoyl chloride is a chemical compound that functions as an acid halide. When used in this capacity, it reacts with various compounds to form esters, amides, and other derivatives. This reaction involves the replacement of the chlorine atom with another functional group, resulting in the formation of new organic compounds. As an acid halide, 2,3-Dichlorobenzoyl chloride is an important reagent in organic synthesis and is widely used in the production of pharmaceuticals, agrochemicals, and other fine chemicals.

4-Fluorobenzoyl chloride

403-43-0sc-238849
sc-238849A
5 g
25 g
$31.00
$56.00
(0)

4-Fluorobenzoyl chloride is a chemical compound that acts as an acid halide. When used in this capacity, it reacts with different compounds to form esters, amides, and other derivatives. This reaction involves the replacement of the chlorine atom with another functional group, resulting in the creation of new organic compounds. As an acid halide, 4-Fluorobenzoyl chloride is an important reagent in organic synthesis and is widely used in the production of pharmaceuticals, agrochemicals, and other fine chemicals.

3-Chlorobenzoyl chloride

618-46-2sc-238523
25 g
$36.00
(0)

3-Chlorobenzoyl chloride is a highly reactive acid halide that is commonly used in organic synthesis. It is known for its ability to undergo rapid acylation reactions with various nucleophiles, leading to the formation of esters, amides, and other important organic compounds. Its unique reactivity and selectivity make it a valuable tool in the production of pharmaceuticals, agrochemicals, and advanced materials. Additionally, 3-Chlorobenzoyl chloride exhibits distinct physical properties, such as its high volatility and low melting point, which make it easy to handle and manipulate in the laboratory. Its specific molecular interactions with nucleophiles and its rapid reaction kinetics make it a versatile and efficient reagent for a wide range of synthetic applications.

4-Methyl-3-(trifluoromethyl)benzoyl chloride

261952-11-8sc-357779
sc-357779A
1 g
5 g
$76.00
$280.00
(0)

4-Methyl-3-(trifluoromethyl)benzoyl chloride is a highly reactive acid halide with unique reactivity and selectivity in organic synthesis. It undergoes rapid acylation reactions with various nucleophiles, leading to the formation of esters, amides, and other important organic compounds. Its distinct physical properties, such as high volatility and low melting point, make it easy to handle and manipulate in the laboratory. The specific molecular interactions with nucleophiles and its rapid reaction kinetics make it a versatile and efficient reagent for a wide range of synthetic applications.

Succinyl chloride

543-20-4sc-258185
25 g
$23.00
(0)

Succinyl chloride is a reactive acid halide that is known for its ability to undergo rapid acylation reactions with a variety of nucleophiles. Its unique reactivity allows for the formation of succinyl derivatives, which are important intermediates in the synthesis of pharmaceuticals, agrochemicals, and polymers. The high reactivity of succinyl chloride also makes it a valuable reagent in the production of succinic acid and its derivatives, which are used in the manufacturing of various industrial products. Additionally, succinyl chloride exhibits distinct physical properties, such as its low boiling point and high solubility in organic solvents, making it a versatile compound for chemical synthesis.

5-Chlorovaleroyl chloride

1575-61-7sc-252263
sc-252263A
10 g
50 g
$99.00
$411.00
(0)

5-Chlorovaleroyl chloride is a reactive acid halide that exhibits rapid acylation reactions with a range of nucleophiles. Its unique reactivity allows for the formation of derivatives, which are crucial intermediates in the synthesis of various chemical compounds. The distinct physical properties of 5-Chlorovaleroyl chloride, such as its low boiling point and high solubility in organic solvents, make it a versatile compound for chemical synthesis and industrial applications. Its specific molecular interactions and reaction kinetics make it a valuable tool in organic synthesis.

2-[3-(trifluoromethyl)phenoxy]propanoyl chloride

sc-335012
100 mg
$100.00
(0)

2-[3-(trifluoromethyl)phenoxy]propanoyl chloride is a highly reactive acid halide that is known for its rapid acylation reactions with a variety of nucleophiles. Its unique reactivity allows for the formation of derivatives, which are important intermediates in the synthesis of various chemical compounds. The distinct physical properties of 2-[3-(trifluoromethyl)phenoxy]propanoyl chloride, such as its low boiling point and high solubility in organic solvents, make it a versatile compound for chemical synthesis and industrial applications.

Malonyl chloride

1663-67-8sc-257688
sc-257688A
5 g
25 g
$48.00
$154.00
(0)

Malonyl chloride is a notable acid halide characterized by its reactivity and ability to form acyl derivatives. It exhibits a high propensity for nucleophilic attack due to the electron-withdrawing effects of the adjacent carbonyl groups, which enhance electrophilicity. This compound undergoes rapid hydrolysis in the presence of water, generating malonic acid and hydrochloric acid. Its distinct dicarbonyl structure allows for unique condensation reactions, facilitating the synthesis of various complex organic molecules.

1,3,5-Benzenetricarbonyl trichloride

4422-95-1sc-251588
sc-251588A
10 g
25 g
$57.00
$79.00
(0)

1,3,5-Benzenetricarbonyl trichloride is a highly reactive acid halide distinguished by its three carbonyl groups, which significantly enhance its electrophilic character. This compound readily participates in nucleophilic acyl substitution reactions, leading to the formation of diverse acyl derivatives. Its unique steric and electronic properties facilitate selective reactions, while its stability under anhydrous conditions allows for controlled reactivity in synthetic pathways. Additionally, it exhibits notable volatility and a low boiling point, making it an intriguing candidate for various chemical transformations.