Date published: 2025-9-28

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Acid Halides

Santa Cruz Biotechnology now offers a broad range of Acid Halides for use in various applications. Acid halides, also known as acyl halides, are a class of organic compounds derived from carboxylic acids by replacing the hydroxyl group (-OH) with a halide group (such as chloride, bromide, or fluoride). These compounds are highly reactive intermediates in organic synthesis due to the electrophilic nature of the carbonyl carbon, which readily undergoes nucleophilic acyl substitution reactions. Acid halides are pivotal in the synthesis of a wide array of chemical compounds, including esters, amides, and anhydrides, making them indispensable in chemical research and industrial processes. In scientific research, acid halides are frequently used to study reaction mechanisms and to develop new synthetic methodologies. Their reactivity also allows for the modification of complex molecules, facilitating the construction of elaborate molecular architectures and the introduction of functional groups that can be further manipulated. Additionally, acid halides play a crucial role in polymer chemistry, where they are used to produce polymers with specific structural and functional properties. Researchers have employed acid halides to explore the synthesis of novel materials, catalysts, and ligands, thereby advancing the fields of materials science, catalysis, and coordination chemistry. The availability of a wide variety of acid halides from Santa Cruz Biotechnology enables researchers to select the appropriate compound for their specific needs, thus driving innovation and discovery in multiple scientific disciplines. View detailed information on our available acid halides by clicking on the product name.

Items 61 to 70 of 374 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Adipoyl chloride

111-50-2sc-357284B
sc-357284
sc-357284A
5 g
25 g
100 g
$29.00
$94.00
$243.00
(0)

Adipoyl chloride is a linear dicarboxylic acid chloride characterized by its ability to engage in multiple acylation reactions due to the presence of two reactive carbonyl groups. This compound demonstrates a high reactivity towards nucleophiles, enabling the formation of polyamide linkages. Its unique structure allows for the formation of cyclic intermediates during reactions, influencing the selectivity and rate of product formation. Additionally, the compound's reactivity can be modulated by varying solvent environments, impacting the overall reaction dynamics.

Octanoyl chloride

111-64-8sc-228878
5 ml
$20.00
(0)

Octanoyl chloride is a saturated fatty acid chloride known for its strong electrophilic nature, which facilitates rapid acylation reactions with nucleophiles. Its linear structure promotes efficient steric interactions, enhancing reaction rates. The compound's reactivity is influenced by the presence of electron-donating or withdrawing groups in the reaction medium, allowing for tailored synthesis pathways. Additionally, it can form stable intermediates, which can lead to diverse product outcomes in organic synthesis.

Decanoyl chloride

112-13-0sc-239656
100 ml
$46.00
(0)

Decanoyl chloride is a long-chain acid chloride characterized by its high reactivity due to the presence of a carbonyl group adjacent to a halogen. This configuration allows for swift nucleophilic acyl substitution, making it a potent acylating agent. Its hydrophobic nature and linear geometry facilitate unique solubility profiles in organic solvents, influencing reaction kinetics. The compound can also engage in transacylation, leading to versatile synthetic routes and diverse functional group transformations.

4-Chlorobenzoyl chloride

122-01-0sc-238818
sc-238818A
5 g
100 g
$30.00
$23.00
(0)

4-Chlorobenzoyl chloride is an aromatic acid chloride distinguished by its electron-withdrawing chlorine substituent, which enhances its electrophilicity. This property accelerates nucleophilic attack, promoting rapid acylation reactions. The compound's planar structure and aromatic character contribute to its stability in various organic media, while its ability to form stable intermediates allows for selective transformations. Additionally, it can participate in Friedel-Crafts acylation, expanding its synthetic utility.

4-Nitrobenzoyl chloride

122-04-3sc-238923
sc-238923A
50 g
250 g
$36.00
$74.00
(0)

4-Nitrobenzoyl chloride is an aromatic acid halide characterized by its strong electron-withdrawing nitro group, which significantly increases its reactivity towards nucleophiles. This heightened electrophilicity facilitates swift acylation processes, making it a potent acylating agent. The compound's rigid planar structure enhances its interaction with nucleophiles, while its ability to form stable acyl intermediates allows for diverse synthetic pathways, including coupling reactions and polymerization.

Azelaic acid dichloride

123-98-8sc-227280
25 g
$88.00
(0)

Azelaic acid dichloride is a saturated aliphatic acid halide known for its unique reactivity profile due to the presence of two chlorine atoms. This configuration enhances its electrophilic character, promoting rapid acylation reactions with nucleophiles. The compound's linear structure allows for effective steric accessibility, facilitating diverse reaction pathways. Its ability to form stable intermediates contributes to its utility in various synthetic applications, including the formation of esters and amides.

2-(Trifluoromethyl)benzoyl chloride

312-94-7sc-223293
sc-223293A
5 g
25 g
$75.00
$272.00
(0)

2-(Trifluoromethyl)benzoyl chloride is a highly reactive acid halide characterized by the presence of a trifluoromethyl group, which significantly enhances its electrophilicity. This unique feature promotes rapid acylation with nucleophiles, leading to efficient formation of acyl derivatives. The strong electron-withdrawing effect of the trifluoromethyl group also influences reaction kinetics, resulting in distinct pathways and intermediates. Its aromatic structure provides additional stability, allowing for selective reactions in complex synthetic environments.

Fluoroacetyl chloride

359-06-8sc-263328
10 g
$890.00
(0)

Fluoroacetyl chloride is a potent acid halide distinguished by its electron-withdrawing fluorine atom, which amplifies its reactivity towards nucleophiles. This heightened electrophilicity facilitates swift acylation reactions, often yielding diverse acyl derivatives. The presence of the fluorine atom also alters the steric and electronic landscape, influencing reaction mechanisms and promoting unique pathways. Its ability to engage in selective reactions makes it a versatile intermediate in synthetic chemistry.

2-Fluorobenzoyl chloride

393-52-2sc-238051
25 g
$44.00
(0)

2-Fluorobenzoyl chloride is a reactive acid halide characterized by its electrophilic nature, which facilitates acylation reactions with nucleophiles. The presence of the fluorine atom enhances its reactivity by stabilizing the carbonyl group through inductive effects, making it a potent acylating agent. Its unique molecular structure allows for selective functionalization in organic synthesis, promoting diverse pathways in the formation of complex molecules. The compound's ability to engage in rapid reaction kinetics further underscores its significance in synthetic chemistry.

2-Bromopropionyl bromide

563-76-8sc-237953
sc-237953A
100 g
500 g
$43.00
$155.00
(0)

2-Bromopropionyl bromide is a highly reactive acid halide known for its strong electrophilic character, which enables efficient acylation with various nucleophiles. The presence of bromine atoms enhances its reactivity, allowing for rapid formation of acyl derivatives. This compound exhibits unique steric properties that influence reaction pathways, promoting regioselectivity in nucleophilic attacks.