Date published: 2025-9-28

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Acid Halides

Santa Cruz Biotechnology now offers a broad range of Acid Halides for use in various applications. Acid halides, also known as acyl halides, are a class of organic compounds derived from carboxylic acids by replacing the hydroxyl group (-OH) with a halide group (such as chloride, bromide, or fluoride). These compounds are highly reactive intermediates in organic synthesis due to the electrophilic nature of the carbonyl carbon, which readily undergoes nucleophilic acyl substitution reactions. Acid halides are pivotal in the synthesis of a wide array of chemical compounds, including esters, amides, and anhydrides, making them indispensable in chemical research and industrial processes. In scientific research, acid halides are frequently used to study reaction mechanisms and to develop new synthetic methodologies. Their reactivity also allows for the modification of complex molecules, facilitating the construction of elaborate molecular architectures and the introduction of functional groups that can be further manipulated. Additionally, acid halides play a crucial role in polymer chemistry, where they are used to produce polymers with specific structural and functional properties. Researchers have employed acid halides to explore the synthesis of novel materials, catalysts, and ligands, thereby advancing the fields of materials science, catalysis, and coordination chemistry. The availability of a wide variety of acid halides from Santa Cruz Biotechnology enables researchers to select the appropriate compound for their specific needs, thus driving innovation and discovery in multiple scientific disciplines. View detailed information on our available acid halides by clicking on the product name.

Items 351 to 360 of 374 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

4-isobutoxy-3-methoxybenzoyl chloride

sc-323159
100 mg
$150.00
(0)

4-Isobutoxy-3-methoxybenzoyl chloride is a notable acid halide characterized by its unique electronic properties and steric effects. The presence of the isobutoxy and methoxy groups enhances its electrophilicity, facilitating swift acylation reactions. This compound demonstrates a remarkable ability to engage in selective nucleophilic attacks, leading to the formation of various acyl derivatives. Its reactivity is further influenced by the spatial arrangement of substituents, allowing for tailored synthetic applications.

(3,5-dimethylphenoxy)acetyl chloride

sc-335870
100 mg
$100.00
(0)

(3,5-Dimethylphenoxy)acetyl chloride is an intriguing acid halide distinguished by its sterically hindered structure, which influences its reactivity profile. The presence of the dimethylphenoxy group enhances its electrophilic character, promoting rapid acylation with nucleophiles. This compound exhibits unique regioselectivity in reactions, allowing for the formation of diverse acyl products. Its distinctive molecular interactions contribute to its behavior in various synthetic pathways, making it a versatile reagent in organic chemistry.

5-ethylthiophene-3-carbonyl chloride

sc-336873
100 mg
$200.00
(0)

5-Ethylthiophene-3-carbonyl chloride is a notable acid halide characterized by its thiophene ring, which imparts unique electronic properties. The presence of the ethyl group enhances steric effects, influencing reaction kinetics and selectivity during acylation processes. This compound readily engages in nucleophilic substitution reactions, showcasing a preference for specific nucleophiles due to its electrophilic carbonyl. Its distinct molecular interactions facilitate diverse synthetic routes, making it a valuable tool in organic synthesis.

[2-(2-Methoxyethoxy)-ethoxy]acetyl chloride

sc-320451
1 g
$745.00
(0)

2-(2-Methoxyethoxy)-ethoxyacetyl chloride is an intriguing acid halide distinguished by its ether functionalities, which enhance solubility and reactivity. The presence of multiple ether groups contributes to its unique steric environment, influencing the reactivity of the acyl chloride. This compound exhibits rapid acylation kinetics, favoring reactions with nucleophiles that can stabilize the resulting intermediates. Its versatile molecular interactions enable a range of synthetic applications, particularly in forming esters and amides.

6-chloro-2-(2-methylphenyl)quinoline-4-carbonyl chloride

sc-337115
100 mg
$150.00
(0)

6-Chloro-2-(2-methylphenyl)quinoline-4-carbonyl chloride is a notable acid halide characterized by its quinoline structure, which introduces unique electronic properties. The chlorine atom enhances electrophilicity, facilitating nucleophilic attack. Its distinct aromatic system allows for selective reactions, while the carbonyl group promotes efficient acylation processes. This compound's reactivity is influenced by steric hindrance from the methyl group, leading to varied reaction pathways in synthetic chemistry.

5-(1,3-Dimethyl-1H-pyrazol-4-yl)-isoxazole-4-sulfonyl chloride

sc-336626
1 g
$745.00
(0)

5-(1,3-Dimethyl-1H-pyrazol-4-yl)-isoxazole-4-sulfonyl chloride stands out as an acid halide due to its unique isoxazole and pyrazole moieties, which contribute to its reactivity profile. The sulfonyl chloride group enhances electrophilic character, making it highly susceptible to nucleophilic substitution. Its distinct molecular architecture allows for selective interactions with various nucleophiles, promoting diverse synthetic routes. The compound's stability under specific conditions further influences its reaction kinetics, enabling controlled transformations in organic synthesis.

3-bromo-4-isopropoxy-5-methoxybenzoyl chloride

sc-335711
100 mg
$150.00
(0)

3-Bromo-4-isopropoxy-5-methoxybenzoyl chloride exhibits notable reactivity as an acid halide, primarily due to its electron-withdrawing bromine and methoxy groups. These substituents enhance the electrophilic nature of the carbonyl carbon, facilitating rapid nucleophilic attack. The steric hindrance from the isopropoxy group influences reaction pathways, allowing for selective substitution reactions. Its unique structural features enable tailored interactions with a variety of nucleophiles, promoting versatile synthetic applications.

4-methoxy-3,5-dimethylbenzenesulfonyl chloride

75157-75-4sc-323200
100 mg
$200.00
(0)

4-Methoxy-3,5-dimethylbenzenesulfonyl chloride functions as a highly reactive acid halide, characterized by its sulfonyl chloride moiety that enhances electrophilicity. The presence of methoxy and dimethyl groups modulates steric effects, influencing the kinetics of nucleophilic substitution. This compound's unique structure allows for selective reactivity with amines and alcohols, promoting diverse synthetic pathways. Its ability to form stable intermediates further facilitates complex reaction mechanisms.

4-[(4-chlorobenzyl)oxy]benzoyl chloride

sc-336219
100 mg
$150.00
(0)

4-[(4-chlorobenzyl)oxy]benzoyl chloride is a potent acid halide distinguished by its electrophilic benzoyl chloride group, which readily engages in nucleophilic acyl substitution reactions. The chlorobenzyl ether moiety introduces steric hindrance, affecting reaction rates and selectivity. This compound's reactivity is enhanced by the resonance stabilization of the acyl chloride, allowing for efficient formation of acyl derivatives. Its unique structure promotes diverse synthetic routes, making it a versatile intermediate in organic synthesis.

2-(2,5-dichlorophenoxy)butanoyl chloride

sc-320519
100 mg
$150.00
(0)

2-(2,5-dichlorophenoxy)butanoyl chloride is a reactive acid halide characterized by its dichlorophenoxy group, which enhances its electrophilicity. This compound exhibits a propensity for nucleophilic attack, leading to rapid acylation reactions. The presence of the bulky dichlorophenyl substituent influences steric factors, potentially modulating reaction kinetics and selectivity. Its unique structure facilitates the formation of various acyl derivatives, making it a valuable intermediate in synthetic chemistry.