Date published: 2025-10-27

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Acid Halides

Santa Cruz Biotechnology now offers a broad range of Acid Halides for use in various applications. Acid halides, also known as acyl halides, are a class of organic compounds derived from carboxylic acids by replacing the hydroxyl group (-OH) with a halide group (such as chloride, bromide, or fluoride). These compounds are highly reactive intermediates in organic synthesis due to the electrophilic nature of the carbonyl carbon, which readily undergoes nucleophilic acyl substitution reactions. Acid halides are pivotal in the synthesis of a wide array of chemical compounds, including esters, amides, and anhydrides, making them indispensable in chemical research and industrial processes. In scientific research, acid halides are frequently used to study reaction mechanisms and to develop new synthetic methodologies. Their reactivity also allows for the modification of complex molecules, facilitating the construction of elaborate molecular architectures and the introduction of functional groups that can be further manipulated. Additionally, acid halides play a crucial role in polymer chemistry, where they are used to produce polymers with specific structural and functional properties. Researchers have employed acid halides to explore the synthesis of novel materials, catalysts, and ligands, thereby advancing the fields of materials science, catalysis, and coordination chemistry. The availability of a wide variety of acid halides from Santa Cruz Biotechnology enables researchers to select the appropriate compound for their specific needs, thus driving innovation and discovery in multiple scientific disciplines. View detailed information on our available acid halides by clicking on the product name.

Items 111 to 120 of 373 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

10-Undecenoyl chloride

38460-95-6sc-237807
25 g
$34.00
(0)

10-Undecenoyl chloride is a distinctive acid halide known for its unsaturated carbon chain, which enhances its reactivity in acylation reactions. The presence of the carbonyl group facilitates electrophilic attack by nucleophiles, while the terminal double bond can participate in additional reactions, such as cross-coupling. This compound's unique structure allows for regioselective reactions, making it a versatile intermediate in synthetic organic chemistry. Its reactivity profile is influenced by steric and electronic factors, enabling tailored synthesis pathways.

Methoxyacetyl chloride

38870-89-2sc-250321
5 g
$20.00
(0)

Methoxyacetyl chloride is a notable acid halide characterized by its methoxy group, which enhances its electrophilic nature. This compound exhibits a propensity for nucleophilic acyl substitution, where the methoxy group can stabilize the transition state, leading to accelerated reaction kinetics. Its unique structure allows for selective functionalization, enabling the formation of diverse derivatives. Additionally, the presence of the acyl chloride moiety promotes reactivity with a variety of nucleophiles, making it a valuable intermediate in synthetic pathways.

1-Bromocarbonyl-1-methylethyl acetate

40635-67-4sc-251484
25 g
$100.00
(0)

1-Bromocarbonyl-1-methylethyl acetate is an intriguing acid halide distinguished by its bromine atom, which significantly influences its reactivity profile. The presence of the carbonyl group enhances electrophilicity, facilitating rapid nucleophilic attack. This compound can engage in unique rearrangement reactions, leading to the formation of various acyl derivatives. Its steric and electronic properties allow for selective interactions with nucleophiles, making it a versatile participant in organic synthesis.

(2,5-Dimethoxyphenyl)acetyl chloride

52711-92-9sc-206534
sc-206534A
1 g
5 g
$40.00
$145.00
1
(0)

(2,5-Dimethoxyphenyl)acetyl chloride is an acid halide distinguished by its methoxy substituents, which enhance its electrophilic character. The presence of these electron-donating groups increases the compound's reactivity towards nucleophiles, allowing for efficient acylation processes. Its unique steric and electronic properties facilitate selective reactions, making it a versatile intermediate in various synthetic routes, particularly in the formation of complex aromatic compounds.

2,2,2-Trichloro-1,1-dimethylethyl chloroformate

66270-36-8sc-238235
5 g
$73.00
(0)

2,2,2-Trichloro-1,1-dimethylethyl chloroformate is an acid halide characterized by its highly reactive chloroformate group, which promotes rapid acylation reactions. The presence of three chlorine atoms enhances its electrophilicity, enabling it to engage with a variety of nucleophiles. This compound exhibits unique reactivity patterns, including the potential for intramolecular interactions, which can lead to the formation of cyclic structures, thereby influencing reaction pathways and kinetics in synthetic chemistry.

2,4,5-Trifluorobenzoyl chloride

88419-56-1sc-238356
5 g
$127.00
(0)

2,4,5-Trifluorobenzoyl chloride is an acid halide distinguished by its trifluoromethyl substituents, which significantly enhance its electrophilic character. This compound readily participates in acylation reactions, exhibiting a preference for nucleophiles with strong electron-donating capabilities. The presence of fluorine atoms can also influence the stability of intermediates, leading to unique reaction kinetics and pathways. Its reactivity is further modulated by steric effects, allowing for selective transformations in complex organic syntheses.

2-Fluoro-6-(trifluoromethyl)benzoyl chloride

109227-12-5sc-225394
1 g
$37.00
(0)

2-Fluoro-6-(trifluoromethyl)benzoyl chloride is an acid halide characterized by its unique trifluoromethyl and fluoro substituents, which impart heightened electrophilicity and reactivity. This compound engages in acylation reactions with a variety of nucleophiles, particularly those with high electron density. The fluorine atoms enhance the stability of transition states, facilitating rapid reaction kinetics. Additionally, the steric hindrance from the trifluoromethyl group allows for selective reactivity, making it a versatile intermediate in organic synthesis.

2-Fluoro-6-iodobenzoyl chloride

111771-12-1sc-225401
5 g
$195.00
(0)

2-Fluoro-6-iodobenzoyl chloride is an acid halide notable for its unique combination of a fluorine and iodine substituent, which significantly influences its reactivity profile. The presence of iodine enhances the electrophilic character, promoting efficient acylation with nucleophiles. This compound exhibits distinctive reaction pathways, often leading to regioselective outcomes due to the interplay of steric and electronic effects. Its ability to form stable intermediates contributes to favorable reaction kinetics, making it a compelling choice in synthetic organic chemistry.

2-Fluoro-4-(trifluoromethyl)benzoyl chloride

126917-10-0sc-225377
5 g
$233.00
(0)

2-Fluoro-4-(trifluoromethyl)benzoyl chloride is an acid halide characterized by its trifluoromethyl group, which imparts strong electron-withdrawing properties. This feature enhances its electrophilicity, facilitating rapid acylation reactions with various nucleophiles. The compound's unique steric environment allows for selective reactions, often yielding specific products. Additionally, its high reactivity can lead to diverse synthetic pathways, making it a versatile intermediate in organic synthesis.

3,5-Difluorobenzoyl chloride

129714-97-2sc-226296
5 g
$68.00
(0)

3,5-Difluorobenzoyl chloride is an acid halide distinguished by its two fluorine substituents, which significantly influence its reactivity and stability. The presence of these electronegative atoms enhances the compound's electrophilic character, promoting swift acylation with nucleophiles. Its unique molecular geometry allows for regioselective reactions, often leading to distinct product distributions. This compound's reactivity profile enables it to participate in a variety of synthetic transformations, showcasing its utility in complex organic synthesis.