ACAD-10 inhibitors interact with a specific enzyme, ACAD-10, which plays a crucial role in various biochemical pathways, primarily involving in the oxidation of fatty acids. ACAD-10 inhibitors are characterized by their ability to bind to the active site of the ACAD-10 enzyme, effectively modulating its activity.
The inhibition of ACAD-10 by these compounds is attributed to their competitive binding nature, where they compete with the natural substrates of the enzyme. This interference disrupts the enzyme's normal catalytic function, leading to downstream effects on related metabolic processes.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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R-(+)-Etomoxir | 124083-20-1 | sc-208201A sc-208201 | 2 mg 5 mg | $245.00 $430.00 | ||
Etomoxir inhibits ACAD-10 by binding to its active site, blocking the entry of long-chain fatty acids into the mitochondria for beta-oxidation, which results in energy deficiency in certain cells, including cancer cells. | ||||||
Ranolazine | 95635-55-5 | sc-212769 | 1 g | $107.00 | 3 | |
Ranolazine indirectly inhibits ACAD-10 by modulating fatty acid oxidation. It decreases fatty acid influx into the mitochondria, leading to improved cardiac efficiency and reduced oxygen consumption in heart cells. | ||||||
1-(2,3,4-Trimethoxybenzyl)piperazine | 5011-34-7 | sc-297236 | 500 mg | $367.00 | ||
Trimetazidine, indirectly affecting ACAD-10, shifts cardiac energy metabolism from fatty acid oxidation towards glucose utilization, thus protecting myocardial cells during ischemic conditions. | ||||||
rac Perhexiline Maleate | 6724-53-4 | sc-460183 | 10 mg | $184.00 | ||
Perhexiline indirectly inhibits ACAD-10 by altering fatty acid metabolism in cardiac cells. It diverts energy production from fatty acid oxidation to glycolysis, offering potential benefits in heart diseases. | ||||||
Ivabradine hydrochloride | 148849-67-6 | sc-507513 | 10 mg | $120.00 | ||
Ivabradine indirectly influences ACAD-10 by reducing heart rate, potentially leading to changes in energy utilization. It is used for angina and heart failure by modifying cardiac function. | ||||||
Meldonium | 76144-81-5 | sc-207887 | 100 mg | $252.00 | 1 | |
Meldonium indirectly affects ACAD-10 by modulating cellular metabolism. It increases glucose consumption, potentially leading to changes in fatty acid utilization and energy production. | ||||||
Hexachlorophene | 70-30-4 | sc-211587 | 1 g | $247.00 | 1 | |
Hexachlorophene, a disinfectant, can interfere with ACAD-10 in some contexts. It's not a specific inhibitor, but its mechanism might involve disruption of enzyme function or cellular processes. | ||||||
Bithionol | 97-18-7 | sc-239383 | 25 g | $77.00 | ||
Bithionol can have non-specific effects on various enzymes, possibly including ACAD-10. Its exact mechanism of action and specificity are not well-documented. |