Glucosidase I Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Castanospermine | 79831-76-8 | sc-201358 sc-201358A | 100 mg 500 mg | $184.00 $632.00 | 10 | |
Castanospermine acts as a glucosidase I inhibitor, showcasing a unique ability to disrupt glycoprotein processing by binding to the enzyme's active site. Its structural conformation allows for specific interactions with key amino acid residues, altering the enzyme's catalytic efficiency. The compound exhibits distinct reaction kinetics, characterized by a competitive inhibition mechanism that influences substrate turnover rates. Additionally, its stereochemistry contributes to selective binding, enhancing its specificity in enzymatic pathways. | ||||||
N-Butyldeoxynojirimycin·HCl | 210110-90-0 | sc-201398 sc-201398A sc-201398B | 5 mg 25 mg 50 mg | $180.00 $550.00 $985.00 | 4 | |
N-Butyldeoxynojirimycin·HCl functions as a glucosidase I inhibitor, exhibiting a unique capacity to modulate glycoprotein biosynthesis. Its molecular structure facilitates strong interactions with the enzyme's active site, leading to significant alterations in enzymatic activity. The compound's kinetic profile reveals a non-competitive inhibition mechanism, impacting substrate affinity and turnover. Furthermore, its solubility characteristics enhance its accessibility in biochemical environments, influencing its interaction dynamics. | ||||||
Acarbose | 56180-94-0 | sc-203492 sc-203492A | 1 g 5 g | $226.00 $605.00 | 1 | |
Acts as a competitive inhibitor of alpha-glucosidases, preventing the breakdown of complex carbohydrates into glucose in the small intestine, thereby reducing post-meal blood sugar spikes. | ||||||
N-Cyclohexylpropyl Deoxynojirimycin | 133342-48-0 | sc-208015 | 2.5 mg | $380.00 | ||
N-Cyclohexylpropyl Deoxynojirimycin acts as a glucosidase I inhibitor, characterized by its ability to disrupt glycan processing pathways. The compound's unique cyclohexyl and propyl substituents enhance its binding affinity to the enzyme, promoting conformational changes that hinder substrate access. Its reaction kinetics suggest a mixed inhibition model, affecting both enzyme activity and substrate binding. Additionally, its hydrophobic properties may influence membrane interactions, altering cellular uptake and distribution. | ||||||
Miglitol | 72432-03-2 | sc-221943 | 10 mg | $161.00 | 1 | |
Inhibits alpha-glucosidases in the small intestine, delaying the digestion of carbohydrates, which lowers the rate of glucose absorption into the bloodstream after meals. | ||||||
Voglibose | 83480-29-9 | sc-204384 sc-204384A | 10 mg 50 mg | $198.00 $681.00 | ||
Works as an alpha-glucosidase inhibitor, slowing the digestion of carbohydrates in the intestine and reducing postprandial blood glucose levels. | ||||||
Deoxynojirimycin | 19130-96-2 | sc-201369 sc-201369A | 1 mg 5 mg | $73.00 $145.00 | ||
Acts as a reversible inhibitor of alpha-glucosidases, hindering the conversion of complex carbohydrates into glucose, thus lowering blood sugar levels post-meal. | ||||||
Zebularine | 3690-10-6 | sc-203315 sc-203315A sc-203315B | 10 mg 25 mg 100 mg | $129.00 $284.00 $1004.00 | 3 | |
An inhibitor of trehalase, a type of glucosidase, which prevents the conversion of trehalose to glucose in certain organisms, impacting carbohydrate metabolism. | ||||||
Isofagomine D-Tartrate | 957230-65-8 | sc-207767 sc-207767A sc-207767C sc-207767B | 5 mg 10 mg 50 mg 25 mg | $387.00 $724.00 $2015.00 $1223.00 | ||
Inhibits glucosylceramidase, an enzyme involved in glycosphingolipid metabolism. | ||||||
Nojirimycin-1-Sulfonic Acid | 114417-84-4 | sc-208102 | 10 mg | $420.00 | ||
Inhibits alpha-glucosidases, preventing the hydrolysis of carbohydrates in the small intestine, thus reducing the rate of glucose absorption following meals. | ||||||