4933427G17Rik Inhibitors
Mfsd13b Inhibitors are a group of compounds that can indirectly modulate the function of the Mfsd13b protein. These inhibitors do not interact with Mfsd13b directly but influence the cellular pathways and processes that Mfsd13b may be involved in. For example, compounds such as glucose and phlorizin can interact with the substrate transport function of Mfsd13b. High concentrations of glucose can lead to the down-regulation of Mfsd13b expression or activity, while phlorizin can alter substrate availability for Mfsd13b by competitively inhibiting similar transporters.
Other compounds, such as nitrendipine and verapamil, can affect the protein indirectly through modulation of calcium homeostasis or by inhibiting drug transport processes that Mfsd13b might participate in. Curcumin and quercetin can influence the protein due to their effects on transport proteins, possibly altering Mfsd13b's activity if it has overlapping substrate specificities. Cyclosporin A and reserpine are examples of compounds that can affect Mfsd13b by their action on multidrug resistance proteins or on vesicular storage mechanisms, respectively. Progesterone represents a hormonal regulation pathway that can affect the expression and activity of Mfsd13b.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
D(+)Glucose, Anhydrous | 50-99-7 | sc-211203 sc-211203B sc-211203A | 250 g 5 kg 1 kg | $38.00 $198.00 $65.00 | 5 | |
Primary substrate for many MFS transporters; high concentrations can down-regulate the expression or activity of MFS-related proteins. | ||||||
Nitrendipine | 39562-70-4 | sc-201466 sc-201466A sc-201466B | 50 mg 100 mg 500 mg | $109.00 $160.00 $458.00 | 6 | |
A dihydropyridine calcium channel blocker that can disrupt calcium homeostasis, possibly affecting Mfsd13b if it is sensitive to intracellular calcium levels. | ||||||
Phloridzin dihydrate | 7061-54-3 | sc-215708 sc-215708A | 250 mg 1 g | $49.00 $119.00 | ||
A competitive inhibitor of glucose transporters belonging to the MFS, which can alter the substrate availability for Mfsd13b if it transports glucose or glucose-like molecules. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
An immunosuppressant that can inhibit multidrug resistance proteins, potentially affecting Mfsd13b if it has a similar structure or function. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
A flavonoid that can influence glucose and other substrate transporters, possibly altering the functioning of Mfsd13b if it transports similar substrates. | ||||||
Fumitremorgin C | 118974-02-0 | sc-202162 | 250 µg | $408.00 | 5 | |
A specific inhibitor of certain MFS transporters, which can affect Mfsd13b if it shares structural similarities. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A natural compound known to modulate the activity of various transport proteins, which can influence Mfsd13b if it has overlapping substrate specificities. | ||||||
Progesterone | 57-83-0 | sc-296138A sc-296138 sc-296138B | 1 g 5 g 50 g | $20.00 $52.00 $298.00 | 3 | |
A steroid hormone known to regulate expression of transporters, which can alter Mfsd13b activity if it is hormonally regulated. | ||||||
Verapamil | 52-53-9 | sc-507373 | 1 g | $374.00 | ||
A calcium channel blocker that can also inhibit certain drug transporters, potentially affecting Mfsd13b if it is involved in drug transport. | ||||||
Reserpine | 50-55-5 | sc-203370 sc-203370A | 1 g 5 g | $137.00 $414.00 | 1 | |
An indole alkaloid that can inhibit vesicular storage of monoamines, potentially affecting Mfsd13b if it plays a role in substrate sequestration. | ||||||