1810043H04Rik Inhibitors encompass a broad spectrum of compounds, each uniquely tailored to modulate the activity or function of the protein 1810043H04Rik, also known as Ndufaf8. While direct inhibitors specific to this protein are not clearly identified, the compounds in this class are conceptualized to target various biochemical pathways and cellular processes that indirectly influence Ndufaf8's functionality. The nature of these inhibitors is diverse, reflecting the complexity of cellular mechanisms and the intricacies of protein regulation. For example, inhibitors within this class include molecules that disrupt mitochondrial function, given Ndufaf8's role in mitochondrial complexes. These inhibitors might function by impairing the electron transport chain, thereby indirectly affecting the activity of Ndufaf8. Additionally, compounds that alter cellular redox states, which are crucial for mitochondrial function, can be part of this class, given the potential impact on Ndufaf8's role within the mitochondria.
Another important aspect of this chemical class involves compounds that modulate the synthesis, stability, and degradation of proteins, impacting Ndufaf8 indirectly. This includes inhibitors that affect protein translation machinery or proteasome function, thereby influencing the overall protein landscape of the cell, including Ndufaf8. Furthermore, compounds that alter signaling pathways linked to mitochondrial biogenesis or stress responses, where Ndufaf8 might play a role, also fall within this category. These inhibitors would operate by altering the upstream signaling mechanisms, thereby modulating the activity or expression of Ndufaf8. The diversity and complexity of these compounds underscore a multifaceted approach to influencing Ndufaf8, leveraging various aspects of cellular function and signaling pathways. Each compound in this theoretical class, with its unique mechanism of action, contributes to the potential modulation of Ndufaf8, highlighting the intricate connections between cellular pathways and protein function.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $254.00 | 41 | |
Inhibits mitochondrial electron transport chain at Complex I, affecting proteins like Ndufaf8. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $54.00 $62.00 $1642.00 $4600.00 | 51 | |
Inhibits Complex III of the mitochondrial electron transport chain, impacting Ndufaf8. | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $146.00 $12250.00 | 18 | |
Inhibits ATP synthase in mitochondria, can affect mitochondrial proteins including Ndufaf8. | ||||||
Carbonyl Cyanide m-Chlorophenylhydrazone | 555-60-2 | sc-202984A sc-202984 sc-202984B | 100 mg 250 mg 500 mg | $75.00 $150.00 $235.00 | 8 | |
Uncouples mitochondrial membrane potential, impacting mitochondrial proteins like Ndufaf8. | ||||||
Sodium azide | 26628-22-8 | sc-208393 sc-208393B sc-208393C sc-208393D sc-208393A | 25 g 250 g 1 kg 2.5 kg 100 g | $42.00 $152.00 $385.00 $845.00 $88.00 | 8 | |
Inhibits Complex IV of the mitochondrial electron transport chain, affecting Ndufaf8. | ||||||
Paraquat chloride | 1910-42-5 | sc-257968 | 250 mg | $149.00 | 7 | |
Induces oxidative stress in mitochondria, can impact mitochondrial proteins including Ndufaf8. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
Inhibits glycolysis, affecting cellular energy metabolism, impacting Ndufaf8 function. | ||||||
FCCP | 370-86-5 | sc-203578 sc-203578A | 10 mg 50 mg | $92.00 $348.00 | 46 | |
Uncouples oxidative phosphorylation in mitochondria, impacting Ndufaf8. | ||||||
Atrazine | 1912-24-9 | sc-210846 | 5 g | $165.00 | 1 | |
Inhibits electron transport in photosynthetic organisms, can indirectly affect mitochondrial function and Ndufaf8. | ||||||
2,4-Dinitrophenol, wetted | 51-28-5 | sc-238345 | 250 mg | $58.00 | 2 | |
Acts as a protonophore, uncoupling oxidative phosphorylation, impacting Ndufaf8. |