Date published: 2025-9-10

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11β-HSD1 Antibodies

Santa Cruz Biotechnology delivers a wide array of 11β-HSD1 monoclonal antibodies for research focused on understanding 11β-hydroxysteroid dehydrogenase type 1. Multiple applications are supported, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). 11β-HSD1 is an essential enzyme responsible for converting cortisone to cortisol, which enables local activation of glucocorticoids within tissues. The enzyme influences numerous physiological processes, including metabolism, stress response, and inflammation. Research has shown that abnormal 11β-HSD1 activity is linked to metabolic disorders, obesity, and various health conditions, highlighting its potential as a therapeutic target. Understanding 11β-HSD1 function and regulation continues to advance medical knowledge in metabolic health and disease treatment. Investigating 11β-HSD1 expression patterns and activity levels provides valuable insights into disease mechanisms and potential therapeutic strategies. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of 11β-HSD1 and its impact on human health.

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11β-HSD1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

11β-HSD1 Antibody (D-5)

sc-518168mouse IgG1 κ90-112 (m)WB, IP, IF, ELISAm, r, h
2
(1)

11β-HSD1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

11β-HSD1 CRISPR/Cas9 KO Plasmid (h)

sc-417313hGene KnockoutGFP0
(0)

11β-HSD1 HDR Plasmid (h)

sc-417313-HDRhHomology Directed RepairPuromycin0
(0)

11β-HSD1 Double Nickase Plasmid (h)

sc-417313-NIChGene KnockoutPuromycin0
(0)

11β-HSD1 Double Nickase Plasmid (h2)

sc-417313-NIC-2hGene KnockoutPuromycin0
(0)

11β-HSD1 CRISPR/Cas9 KO Plasmid (m)

sc-420958mGene KnockoutGFP0
(0)

11β-HSD1 HDR Plasmid (m)

sc-420958-HDRmHomology Directed RepairPuromycin0
(0)

11β-HSD1 Double Nickase Plasmid (m)

sc-420958-NICmGene KnockoutPuromycin0
(0)

11β-HSD1 Double Nickase Plasmid (m2)

sc-420958-NIC-2mGene KnockoutPuromycin0
(0)

11β-HSD1 CRISPR Activation Products

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11β-HSD1 CRISPR Activation Plasmid (h)

sc-417313-ACThGene ActivationPuro, Blast, Hygro0
(0)

11β-HSD1 CRISPR Activation Plasmid (h2)

sc-417313-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

11β-HSD1 Lentiviral Activation Particles (h)

sc-417313-LAChGene ActivationPuro, Blast, Hygro0
(0)

11β-HSD1 Lentiviral Activation Particles (h2)

sc-417313-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

11β-HSD1 CRISPR Activation Plasmid (m)

sc-420958-ACTmGene ActivationPuro, Blast, Hygro0
(0)

11β-HSD1 CRISPR Activation Plasmid (m2)

sc-420958-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

11β-HSD1 Lentiviral Activation Particles (m)

sc-420958-LACmGene ActivationPuro, Blast, Hygro0
(0)

11β-HSD1 Lentiviral Activation Particles (m2)

sc-420958-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

11β-HSD1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

11β-HSD1 siRNA (h)

sc-41377hGene SilencingN/A0
(0)

11β-HSD1 shRNA Plasmid (h)

sc-41377-SHhGene SilencingPuromycin0
(0)

11β-HSD1 shRNA (h) Lentiviral Particles

sc-41377-VhGene SilencingPuromycin0
(0)

11β-HSD1 siRNA (m)

sc-41378mGene SilencingN/A0
(0)

11β-HSD1 shRNA Plasmid (m)

sc-41378-SHmGene SilencingPuromycin0
(0)

11β-HSD1 shRNA (m) Lentiviral Particles

sc-41378-VmGene SilencingPuromycin0
(0)