VEZF1 Antibody (D-8): sc-365566
- VEZF1 Antibody (D-8) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against amino acids 351-516 mapping at the C-terminus of VEZF1 of human origin
- recommended for detection of VEZF1 of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-365566 X, 200 µg/0.1 ml)
- m-IgG2b BP-HRP is the preferred secondary detection reagent for VEZF1 Antibody (D-8) for WB applications. This reagent is now offered in a bundle with VEZF1 Antibody (D-8) (see ordering information below).
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VEZF1 Antibody (D-8) is a mouse monoclonal IgG2b antibody that detects VEZF1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). VEZF1, also known as ZNF161 or DB1, is a crucial nuclear-localizing zinc-finger protein that plays a significant role in the regulation of endothelial gene expression, particularly in vascular development. VEZF1 is predominantly expressed in the kidneys and skeletal muscle, where VEZF1 functions as a transcription factor that modulates the expression of endothelin-1 (ET-1) by binding to the CT/GC-rich region of the ET-1 promoter. VEZF1′s ability to activate ET-1 expression is vital for proper assembly of the cardiovascular system during early embryonic development, as VEZF1 influences the expression of various genes essential for vascular endothelial function. Additionally, VEZF1′s interaction with the KRAB domain and KAP1 highlights VEZF1′s role in recruiting histone-modifying proteins, further emphasizing VEZF1′s importance in transcriptional regulation and chromatin remodeling. With diverse functions and critical involvement in cardiovascular development, VEZF1 is a key target for research in vascular biology and related fields.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
VEZF1 Antibody (D-8) | sc-365566 | 200 µg/ml | $322.00 | |||
VEZF1 Antibody (D-8): m-IgG2b BP-HRP Bundle | sc-548557 | 200 µg Ab; 10 µg BP | $361.00 | |||
VEZF1 Antibody (D-8) X | sc-365566 X | 200 µg/0.1 ml | $322.00 |