Date published: 2025-9-7

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TSPAN8 抗体 (1E5): sc-293317

5.0(1)
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说明书
  • TSPAN8抗体(1E5)是小鼠单克隆IgG3 λ TSPAN8抗体, 在1篇文献中引用,规格为50 µg/0.5 ml
  • 针对110-205的氨基酸TSPAN8的氨基酸human的氨基酸
  • 推荐用于 human 来源的TSPAN8 WB, IP, IF, IHC(P) 和 ELISA检测
  • 目前,我们还没有完成TSPAN8 抗体 (1E5)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

TSPAN8抗体(1E5)是一种小鼠单克隆IgG3抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)、石蜡包埋切片免疫组织化学(IHCP)和酶联免疫吸附测定(ELISA)检测人类TSPAN8蛋白。抗TSPAN8抗体(1E5)以非结合形式提供。TSPAN8,也称为四聚体蛋白8、TM4SF3或CO-029,是一种237个氨基酸的多肽膜蛋白,属于跨膜蛋白的四聚体蛋白家族。 TSPAN8对于促进细胞间相互作用至关重要,并参与多种细胞过程,包括信号转导,影响细胞发育、激活、生长和运动。TSPAN8主要定位于细胞膜,在多种癌症(包括结肠癌、胃癌、肾癌和胰腺癌)中均有表达,表明其在癌症进展和转移中起着重要作用。编码TSPAN8的基因位于人类第12号染色体上,该区域包含1100多个基因,与软骨发育不全和诺南综合征等多种疾病有关。了解TSPAN8的功能和相互作用至关重要,因为TSPAN8可能成为癌症诊断的潜在生物标记物和治疗干预的目标。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

TSPAN8 抗体 (1E5) 参考文献:

  1. 在破坏四跨相互作用的条件下,选择性四跨-整合素复合物(CD81/alpha4beta1, CD151/alpha3beta1, CD151/alpha6beta1)。  |  Serru, V., et al. 1999. Biochem J. 340 (Pt 1): 103-11. PMID: 10229664
  2. 肝细胞癌中四泛素 CO-029 的过表达。  |  Kanetaka, K., et al. 2001. J Hepatol. 35: 637-42. PMID: 11690710
  3. 四跨蛋白与整合素的复合物:远不止表面所见。  |  Berditchevski, F. 2001. J Cell Sci. 114: 4143-51. PMID: 11739647
  4. 在 4,516 名葡萄糖耐受性良好的丹麦中年人群样本中,对 JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9 和 NOTCH2 基因位点中的新型 2 型糖尿病风险等位基因与胰岛素释放, 胰岛素敏感性和肥胖进行关联测试。  |  Grarup, N., et al. 2008. Diabetes. 57: 2534-40. PMID: 18567820
  5. 人类肿瘤相关抗原 CO-029 的 cDNA 分子克隆及相关跨膜抗原的鉴定。  |  Szala, S., et al. 1990. Proc Natl Acad Sci U S A. 87: 6833-7. PMID: 2395876
  6. 跨膜 4 超家族成员 Cd63 的基因定域揭示了小鼠基因组中两个不同的基因位点。  |  Gwynn, B., et al. 1996. Genomics. 35: 389-91. PMID: 8661157

订购信息

产品名称产品编号规格价格数量收藏夹

TSPAN8 抗体 (1E5)

sc-293317
50 µg/0.5 ml
$316.00

Do you recommend using reducing or non-reducing conditions for this antibody 1E5?

Asked by: Julia
Thank you for your question . We recommend reducing conditions.
Answered by: BlakeJ
Date published: 2024-11-22

are there some papers in which the TSPAN8 (1E5): sc-293317 is used?

Asked by: Jiang MIn
Thank you for your question. Unfortunately we are not aware of any publications using TSPAN8 (1E5): sc-293317 at this time.
Answered by: Tech Service
Date published: 2019-10-10

Can you provide some IHC images? Because it is not clear from the IF image that it shows membrane localization or not. Thanks!

Asked by: XiaoJ
This mouse monoclonal antibody is recommended and warrantied for immunohistochemistry (IF and IHC(P)), however we are still gathering data to show on our website. Check back for updates!
Answered by: Technical Support
Date published: 2019-02-11

May I ask for a test sample of this monoclonal antibody? Thanks!

Asked by: XiaoJ
Thank you for your question. This antibody is not currently available in a sample size. It is available for purchase only. We do warranty the antibody to perform in the indicated species and research applications.
Answered by: Technical Support
Date published: 2019-02-11

I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with TSPAN8 (1E5): sc-293317 monoclonal antibody?

Asked by: AbPolly
We recommend using one of our our exclusive Mouse IgG Binding Proteins (m-IgGλ) conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support
Date published: 2017-02-27
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Rated 5 out of 5 by from Good specificity for TSPAN8 in Western BlotThis antibody detects over-expressed human TSPAN8 in a transfected lysate. -SCBT QC
Date published: 2023-09-14
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TSPAN8 抗体 (1E5) is rated 5.0 out of 5 by 1.
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