TLR2 Antibody (11G7): sc-47728
- TLR2 Antibody (11G7) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
- raised against human TLR2
- recommended for detection of TLR2 of human origin by IP and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also provided azide-free for biological studies, sc-47728 L, 200 µg/0.1 ml
- See TLR2 (TL2.1): sc-21759 for TLR2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TLR2 Antibody (11G7). These reagents are now offered in bundles with TLR2 Antibody (11G7) (see ordering information below).
TLR2 Antibody (11G7) is a mouse monoclonal IgG1 antibody that detects TLR2 in human samples through applications such as immunoprecipitation (IP) and flow cytometry (FCM). TLR2, a member of the Toll-like receptor family, plays a crucial role in the innate immune response by recognizing pathogen-associated molecular patterns, particularly lipopolysaccharides and peptidoglycans from bacteria. This recognition is vital for initiating inflammatory responses and activating immune cells, thereby contributing to the host′s defense against infections. TLR2 is predominantly expressed on the surface of immune cells, including macrophages and dendritic cells, where TLR2 acts as a sentinel for microbial invasion. Upon ligand binding, TLR2 dimerizes with other TLRs, such as TLR1 or TLR6, leading to the recruitment of adaptor proteins and the activation of downstream signaling pathways, including the NF-kB pathway. This signaling cascade results in the production of pro-inflammatory cytokines, which are essential for orchestrating an effective immune response. TLR2′s ability to modulate immune responses makes TLR2 a critical target for therapeutic interventions aimed at enhancing or regulating immunity in various diseases, including infections and autoimmune disorders. Anti-TLR2 antibody (11G7) serves as an invaluable tool for researchers studying the mechanisms of immune activation and the role of TLRs in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TLR2 Antibody (11G7) | sc-47728 | 200 µg/ml | $322.00 | |||
TLR2 Antibody (11G7): m-IgG Fc BP-HRP Bundle | sc-536803 | 200 µg Ab; 10 µg BP | $361.00 | |||
TLR2 Antibody (11G7): m-IgGκ BP-HRP Bundle | sc-533967 | 200 µg Ab; 40 µg BP | $361.00 | |||
TLR2 Antibody (11G7): m-IgG1 BP-HRP Bundle | sc-544828 | 200 µg Ab; 20 µg BP | $361.00 | |||
TLR2 Antibody (11G7) FITC | sc-47728 FITC | 200 µg/ml | $336.00 | |||
TLR2 Antibody (11G7) L | sc-47728 L | 200 µg/0.1 ml | $322.00 | |||
TLR2 Antibody (11G7) PE | sc-47728 PE | 200 µg/ml | $349.00 |