TCR V β 7 Antibody (TR310): sc-53149
- TCR V β 7 Antibody (TR310) is a rat monoclonal IgG2b provided at 200 µg/ml
- raised against TK1 cell line of mouse origin
- recommended for detection of TCR V β 7 bearing T cells of mouse origin by WB and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for TCR V β 7 Antibody (TR310). This work is in progress.
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TCR V β 7 Antibody (TR310) is a rat monoclonal IgG2b antibody that detects T cell receptor V β 7 (TCR V β 7) in mouse samples through flow cytometry (FCM). TCR V β 7 plays a crucial role in the immune response by recognizing specific antigens presented by major histocompatibility complex (MHC) molecules, which is essential for T cell activation and subsequent immune function. TCR V β 7 is primarily located on the surface of T cells, where TCR V β 7 forms part of the T cell receptor complex, allowing T cells to distinguish between self and non-self antigens. TCR V β 7′s ability to recognize a diverse array of antigens is vital for the adaptive immune system, as this recognition enables the body to mount effective responses against various pathogens. Additionally, TCR V β 7 is involved in the regulation of T cell development and differentiation, making TCR V β 7 a key player in maintaining immune homeostasis. Anti-TCR V β 7 antibody (TR310) is an invaluable tool for researchers studying T cell biology, immune responses, and the development of T cell-related diseases, including lymphomas.
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TCR V β 7 Antibody (TR310) References:
- Restricted TCR V beta gene expression and enterovirus infection in type I diabetes: a pilot study. | Luppi, P., et al. 2000. Diabetologia. 43: 1484-97. PMID: 11151757
- T cells engrafted with a recombinant anti-CD30 receptor target autologous CD30(+) cutaneous lymphoma cells. | Hombach, A., et al. 2001. Gene Ther. 8: 891-5. PMID: 11423937
- Human invariant V alpha 24-J alpha Q TCR supports the development of CD1d-dependent NK1.1+ and NK1.1- T cells in transgenic mice. | Capone, M., et al. 2003. J Immunol. 170: 2390-8. PMID: 12594262
- H-2 class I Ld antigen positively selects different TCR V beta gene products in CD8+ and CD4+ T cells. | Tscherning, T., et al. 1992. Scand J Immunol. 36: 617-9. PMID: 1357740
- Effect of Hejie decoction on T cell immune state of chronic hepatitis B patients. | Zhang, SJ., et al. 2004. World J Gastroenterol. 10: 1436-9. PMID: 15133849
- Identification of HLA class I dependent immunogenic peptides from clonotypic TCRbeta expressed in cutaneous T-cell lymphoma. | Zeng, J., et al. 2006. Int J Cancer. 119: 2476-80. PMID: 16858680
- CD1d expression on chronic lymphocytic leukemia B cells affects disease progression and induces T cell skewing in CD8 positive and CD4CD8 double negative T cells. | Zaborsky, N., et al. 2016. Oncotarget. 7: 49459-49469. PMID: 27385215
- Evidence for superantigen involvement in insulin-dependent diabetes mellitus aetiology. | Conrad, B., et al. 1994. Nature. 371: 351-5. PMID: 8090207
- Enhanced prevalence of T cell receptor V beta 7 gene family expression in human intestine-associated T lymphocytes. | Esin, S., et al. 1996. Immunol Lett. 51: 149-55. PMID: 8832283
- Heligmosomoides polygyrus superantigen: differential response with mouse and human lymphocytes. | Robinson, M. and Gustad, TR. 1997. Parasitology. 115 (Pt 5): 531-6. PMID: 9368904
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TCR V β 7 Antibody (TR310) | sc-53149 | 200 µg/ml | $322.00 | |||
TCR V β 7 Antibody (TR310) FITC | sc-53149 FITC | 200 µg/ml | $336.00 | |||
TCR V β 7 Antibody (TR310) PE | sc-53149 PE | 200 µg/ml | $349.00 |