Suppressin Antibody (C-8): sc-398387
- Suppressin Antibody (C-8) is a mouse monoclonal mouse IgG3 κ κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 119-134 within an internal region of Suppressin of human origin
- recommended for detection of Suppressin of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, porcine and avian
- m-IgG3 BP-HRP is the preferred secondary detection reagent for Suppressin Antibody (C-8) for WB applications. This reagent is now offered in a bundle with Suppressin Antibody (C-8) (see ordering information below).
QUICK LINKS
SEE ALSO...
Suppressin Antibody (C-8) is a mouse monoclonal IgG3 antibody that detects Suppressin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Suppressin, also known as DEAF1, SPN, NUDR, or ZMYND5, is a crucial transcription factor involved in embryonic development, characterized by its SAND domain and C-terminal MYND-type zinc finger structure. This unique structure enables Suppressin (C-8) antibody to interact with other proteins, such as LMO4 and CLIM-2, which are vital for mediating cell fate decisions and embryonic pattern formation. Nuclear localization of anti-Suppressin antibody (C-8) underscores Suppressin′s role in regulating gene expression during development. Several isoforms due to alternative splicing allow for functional diversity, with some isoforms being secreted to inhibit cell proliferation by arresting cells in the G0 or G1 phase. Mutations in the gene encoding Suppressin can confer a growth advantage to cells, potentially leading to neoplasia, making Suppressin a promising target for cancer therapy. Anti-Suppressin antibody (C-8) serves as an invaluable tool for researchers studying the intricate roles of Suppressin in development and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Suppressin Antibody (C-8) | sc-398387 | 200 µg/ml | $322.00 | |||
Suppressin Antibody (C-8): m-IgG3 BP-HRP Bundle | sc-550507 | 200 µg Ab; 40 µg BP | $361.00 | |||
Suppressin (C-8) Neutralizing Peptide | sc-398387 P | 100 µg/0.5 ml | $69.00 |