Date published: 2025-9-7

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SCG10 抗体 (2-RE19): sc-135620

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说明书
  • SCG10 抗体 2-RE19 是小鼠单克隆 IgG2b κ,SCG10抗体, 在5篇文献中引用,规格为100 µg/ml
  • 针对human重组SCG10蛋白的抗原性氨基酸
  • 推荐用于 mouse, rat 和 human 来源的SCG10 WB, IP 和 ELISA检测
  • 关于如何获取SCG10 (2-RE19): sc-135620免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前,我们还没有完成SCG10 抗体 (2-RE19)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

SCG10抗体(2-RE19)是一种IgG2b κ型小鼠单克隆SCG10抗体(也称为SCG10抗体),能够通过蛋白质印迹(WB)、免疫沉淀(IP)和酶联免疫吸附测定(ELISA)检测小鼠、大鼠和人类来源的SCG10蛋白。SCG10抗体(2-RE19)以非偶联形式的抗SCG10抗体提供。SCG10,也被称为stathmin-like 2(STMN2),是一种属于stathmin家族的神经元生长相关蛋白(nGAP)。Stathmin家族磷蛋白参与微管动力学和信号转导的调节。SCG10与膜相关且具有神经元特异性,可能参与神经元分化,并可能在神经突生长过程中调节膜与细胞骨架的相互作用。SCG10蛋白与微管结合并抑制其组装,还可以诱导微管解聚。微管的组装和解聚对于细胞分裂、细胞内运输和细胞运动以及发育中的神经系统的神经突伸长、生长和分支都是必要的。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

SCG10 抗体 (2-RE19) 参考文献:

  1. Stathmin 家族蛋白具有特定的分子和微管蛋白结合特性。  |  Charbaut, E., et al. 2001. J Biol Chem. 276: 16146-54. PMID: 11278715
  2. 神经元生长缔合作用, 微管稳定因子 SCG10 在脑衍生物筏膜微域中的定域。  |  Maekawa, S., et al. 2001. J Biochem. 129: 691-7. PMID: 11328590
  3. 对转基因小鼠 SCG10 基因表达的分析表明,神经特异性是通过选择性去抑制实现的。  |  Wuenschell, CW., et al. 1990. Neuron. 4: 595-602. PMID: 2322463
  4. NGF诱导的SCG10 mRNA编码一种新型膜结合蛋白,存在于生长锥中,在发育中的神经元中含量丰富。  |  Stein, R., et al. 1988. Neuron. 1: 463-76. PMID: 3272176
  5. 神经元生长相关蛋白 SCG10 对微管动力学的调控  |  Riederer, BM., et al. 1997. Proc Natl Acad Sci U S A. 94: 741-5. PMID: 9012855

订购信息

产品名称产品编号规格价格数量收藏夹

SCG10 抗体 (2-RE19)

sc-135620
100 µg/ml
$333.00

Can we use it for Immunocytochemistry?

Asked by: Shringika
Thank you for your question. SCG10 Antibody (2-RE19): sc-135620 is recommended for detection of SCG10 of mouse, rat and human origin by WB, IP and ELISA. We do not recommend it for use in cytochemistry.
Answered by: Tech Support Europe
Date published: 2025-05-09

Do you have an scg10 antibody that identifies the n terminus of the protein ? 

Asked by: Lesliealanna
Thank you for your question. This antibody was raised against a recombinant protein mapping within amino acids 73-179 of SCG10 of human origin (accession#Q93045) .
Answered by: Tech Service
Date published: 2020-02-19

For Western Blot, is it recommended to use denatured or non-denatured conditions with SCG10 (2-RE19): sc-135620 antibody?

Asked by: jerojero
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-03-27
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Rated 5 out of 5 by from Good choice for immunoprecipitationAntibody has been used for Immunoprecipitation in published research. -SCBT QC
Date published: 2023-09-14
Rated 4 out of 5 by from Good for IFThis SCG10 Antibody (2-RE19), sc-135620, shows strong specific signal in IF staining in primary rat motor neuron.
Date published: 2018-02-20
Rated 4 out of 5 by from WB and IP publishable data with human gastricWB and IP publishable data with human gastric cancer cell lines SGC-7901, MGC-803, BGC-823, AGS, MKN1,MKN45, normal gastric epithelial cell line GES-1 and human embryonic kidney 293 (HEK-293) - SCBT Publication Review
Date published: 2014-07-21
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SCG10 抗体 (2-RE19) is rated 4.3 out of 5 by 3.
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