SB 221284 (CAS 196965-14-7)

物理状态 :

Solid

溶解度 :

Soluble in DMSO (100 mM).

保存 :

Store at room temperature

熔点 :

193.26° C (Predicted)

沸点 :

536.21° C at 760 mmHg (Predicted)

密度 :

1.44 g/cm³ (Predicted)

折射率 :

n²⁰_D 1.62 (Predicted)

IC50 :

CYP1A2: IC₅₀ = 13 nM (human); CYP2D6: IC₅₀ = 110 nM (human); CYP2C9: IC₅₀ = >100 µM (human); CYP3A4: IC₅₀ = >100 µM (human); CYP19: IC₅₀ = >100 µM (human)

pK值 :

pK_a: 13.13 (Predicted), pK_b: 5.03 (Predicted)

德国水公害等级 :

3

PubChem CID :

MDL 号码 :

MFCD00950075

SMILES :

CSC1=C(C=C2N(CCC2=C1)C(=O)NC1=CC=CN=C1)C(F)(F)F