Rab 33A/B Antibody (D-12): sc-271199

Rab 33A/B Antibody (D-12) is a mouse monoclonal IgG2b kappa light chain antibody that detects Rab 33A/B protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Rab 33A/B antibody (D-12) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Rab 33A/B protein plays a crucial role in intracellular transport processes, particularly in the movement of vesicles between the endoplasmic reticulum and the Golgi apparatus, which is essential for proper protein secretion. This transport maintains cellular function and homeostasis by ensuring proteins are correctly modified and delivered to intended destinations. Rab 33A and Rab 33B, while sharing conserved effector domains, exhibit only 55.3% overall amino acid identity, indicating potential interactions with similar effector and regulatory proteins, which could influence distinct roles in cellular processes. Notably, Rab 33B is widely expressed and participates in intra-Golgi transport, while Rab 33A is predominantly found in CD8+ T cells and has been implicated in immune response to tuberculosis. Rab 33A/B (D-12) monoclonal antibody′s versatility in various applications makes Rab 33A/B (D-12) antibody an invaluable tool for researchers studying protein transport dynamics and functional roles of Rab proteins in different biological contexts.

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LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Rab 33A/B Antibody (D-12) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-Rab 33A/B Antibody (D-12) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Rab 33A/B Antibody (D-12) Specifications

Alternate Product Name: Rab 33A/B

Product Clone Name: D-12

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids: 35-75

Epitope Target: Rab 33A/B

Epitope Species: human

Product Reactivity/Detection: Rab 33A and Rab 33B

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for Rab 33A/B Antibody (D-12): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin