PYK2 Antibody (F-6): sc-74539
- PYK2 Antibody (F-6) is a mouse monoclonal IgA κ, cited in 4 publications, provided at 200 µg/ml
- raised against amino acids 1-102 mapping at the N-terminus of PYK2 of human origin
- recommended for detection of PYK2 of mouse, rat and human origin by WB, IP, IF and ELISA
- See PYK2 (E-3): sc-393181 for PYK2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for PYK2 Antibody (F-6). This work is in progress.
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SEE ALSO...
PYK2 Antibody (F-6) is a mouse monoclonal IgA antibody that detects PYK2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PYK2, also known as proline-rich tyrosine kinase 2, plays a crucial role in cellular signaling, particularly in the central nervous system where PYK2 is highly expressed. PYK2 is involved in the modulation of ion channel function and the activation of the mitogen-activated protein kinase (MAPK) signaling pathway, which are essential for various cellular responses, including growth, differentiation, and survival. PYK2 activation occurs rapidly in response to stimuli that elevate intracellular calcium levels, as well as through the action of phorbol esters that activate protein kinase C (PKC) family members. Notably, PYK2 undergoes post-translational modifications, including phosphorylation on tyrosine residues, which are critical for function and regulation. The unique structural organization of PYK2, with a high degree of sequence identity to focal adhesion kinase (FAK), underscores PYK2′s importance in cellular signaling networks and highlights PYK2′s potential as a therapeutic target in various diseases. Anti-PYK2 antibody (F-6) is an invaluable tool for researchers studying the intricate roles of this kinase in cellular processes and disease mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PYK2 Antibody (F-6) | sc-74539 | 200 µg/ml | $322.00 |