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PXR 抗体 (H-11): sc-48340

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说明书
  • PXR抗体(H-11)是小鼠单克隆IgG2b κ, 在43篇文献中引用,规格为200 µg/ml
  • 免疫human物种的PXR的氨基酸101-260
  • PXR 抗体 (H-11) 推荐用于WB, IP, IF 和 ELISA,检测human 来源的 PXR.1 and PXR.2
  • 抗PXR抗体(H-11)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 可用于凝胶迁移和ChIP的TransCruz试剂(sc-48340 X, 200 µg/0.1 ml)
  • 关于如何获取PXR (H-11): sc-48340免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP2b BP-HRP">m-IgG2b BP-HRP是PXR Antibody (H-11) 适用于 WB 应用。 的首选辅助检测试剂,这些试剂现与PXR Antibody (H-11) 打包提供(请参阅下面的订购信息)。

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関連項目

PXR抗体(H-11)是一种小鼠单克隆IgG2b kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和酶联免疫吸附测定(ELISA)等方法检测人体样本中的PXR。PXR (H-11) 抗体有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶 (HRP)、藻红蛋白 (PE)、异硫氰酸荧光素 (FITC) 和多种 Alexa Fluor® 结合物。孕烷X受体(Pregnane X Receptor,PXR)在基因表达调控中起着至关重要的作用,它充当多种内源性和外源性化合物(包括类固醇和药物)的传感器。PXR主要位于细胞核中,作为转录因子与配体结合后,与类维生素A X受体(retinoid X receptor,RXR)形成异二聚体,随后与特定的DNA序列结合,从而调节药物代谢和转运相关靶基因的表达。这种定位使PXR能够直接影响细胞对各种物质的反应,从而在药物基因组学和人体处理药物的能力方面发挥重要作用。PXR有两种同工型,即PXR.1和PXR.2,它们可能具有不同的调节功能,进一步强调了PXR在调节合成糖皮质激素和其他不通过经典糖皮质激素受体途径起作用的化合物的作用方面的重要性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

PXR 抗体 (H-11)

sc-48340
200 µg/ml
$316.00

PXR (H-11): m-IgG Fc BP-HRP 套装

sc-525559
200 µg Ab; 10 µg BP
$354.00

PXR (H-11): m-IgG2b BP-HRP 套装

sc-549582
200 µg Ab; 10 µg BP
$354.00

PXR 抗体 (H-11) X

sc-48340 X
200 µg/0.1 ml
$316.00

PXR 抗体 (H-11) AC

sc-48340 AC
500 µg/ml, 25% agarose
$416.00

PXR 抗体 (H-11) HRP

sc-48340 HRP
200 µg/ml
$316.00

PXR 抗体 (H-11) FITC

sc-48340 FITC
200 µg/ml
$330.00

PXR 抗体 (H-11) PE

sc-48340 PE
200 µg/ml
$343.00

PXR 抗体 (H-11) Alexa Fluor® 488

sc-48340 AF488
200 µg/ml
$357.00

PXR 抗体 (H-11) Alexa Fluor® 546

sc-48340 AF546
200 µg/ml
$357.00

PXR 抗体 (H-11) Alexa Fluor® 594

sc-48340 AF594
200 µg/ml
$357.00

PXR 抗体 (H-11) Alexa Fluor® 647

sc-48340 AF647
200 µg/ml
$357.00

PXR 抗体 (H-11) Alexa Fluor® 680

sc-48340 AF680
200 µg/ml
$357.00

PXR 抗体 (H-11) Alexa Fluor® 790

sc-48340 AF790
200 µg/ml
$357.00

hi All of you, Do you know if you this antibody could detect the dimer of hPXR ?

Asked by: Alessandro G
Thank you for your question. Please Contact our Technical Service for additional information regarding this antibody.
Answered by: SCBT Heidelberg Support
Date published: 2018-12-22

When should the TransCruz reagent sc-48340 X be used instead of the standard form sc-48340?

Asked by: jerojero
Thank you for your question. We recommend using the TransCruz reagent form when performing ChIP or GelShift assays. This form can also be used in other applications such as Western Blot or IHC, but the dilution should be adjusted by a factor of 10 to account for the higher original concentration.
Answered by: Technical Support
Date published: 2017-02-24
  • y_2025, m_9, d_6, h_5CST
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Rated 3 out of 5 by from FonctionneEn WB cet anticorps fonctionne malgré des bandes contaminantes. Il permet aussi de faire une IP mais pas de très bonne qualité.
Date published: 2019-02-20
Rated 5 out of 5 by from Publishable data for IHCPublishable data for IHC, ICC and WB in human breast tissues, MDA-MB-231 cells, MCF7 cells -SCBT Publication Review
Date published: 2015-07-10
Rated 5 out of 5 by from Published data for WB in human LS180 cellsPublished data for WB in human LS180 cells. -SCBT Publication Review
Date published: 2015-06-15
Rated 5 out of 5 by from Published data for WB in human hepatocytesPublished data for WB in human hepatocytes and HepG2 cells. -SCBT Publication Review
Date published: 2015-05-24
Rated 5 out of 5 by from Published data for WB in monkey CVPublished data for WB in monkey CV-1 cells. -SCBT Publication Review
Date published: 2015-01-31
Rated 5 out of 5 by from Strong positive signal seen in WB in humanStrong positive signal seen in WB in human PXR transfected 293 whole cell lysates. -SCBT QC
Date published: 2013-01-08
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PXR 抗体 (H-11) is rated 4.7 out of 5 by 6.
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