Date published: 2025-9-6

021-6093-6350

SCBT Portrait Logo
Seach Input

PTH-rP 抗体 (1D1): sc-53936

4.7(9)
寫評論提問

说明书
  • PTH-rP 抗体 1D1 是小鼠单克隆 IgG1PTH-rP抗体, 在9篇文献中引用,规格为200 µg/ml
  • 针对全长PTH-rP,human起源
  • PTH-rP 抗体 (1D1) 推荐用于WB, IP, IF, IHC(P) 和 ELISA,检测human 来源的 PTH-rP
  • 抗PTH-rP抗体(1D1)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取PTH-rP (1D1): sc-53936免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前,我们还没有完成PTH-rP 抗体 (1D1)的首选二抗检测试剂的鉴定。这项工作正在进行中。

快捷链接

関連項目

PTH-rP 抗体 (1D1) 是一种小鼠单克隆 IgG1 抗体,可通过免疫印迹 (WB)、免疫沉淀 (IP)、免疫荧光 (IF)、石蜡包埋切片免疫组织化学 (IHCP) 和酶联免疫吸附试验 (ELISA) 检测人源 PTH-rP 蛋白。PTH-rP (1D1) 抗体有非共轭型和多种共轭型,包括琼脂糖、辣根过氧化物酶 (HRP)、藻红蛋白 (PE)、异硫氰酸荧光素 (FITC) 和多种 Alexa Fluor® 共轭物。甲状旁腺激素相关蛋白(PTH-rP)在调节软骨内骨发育中起着至关重要的作用,并参与上皮-间质相互作用,尤其是在乳腺和牙齿的形成过程中。与完全由甲状旁腺细胞合成的甲状旁腺激素(PTH)不同,PTH-rP 由多种类型的细胞产生,具有多种生理作用。PTH-rP 在恶性肿瘤的体液性高钙血症中尤为重要,PTH-rP 可模拟 PTH 的作用,导致血钙水平升高。PTH 和 PTH-rP 都受维生素 D 和类固醇激素的影响,通过与特定的 PTH/PTH-rP 受体结合产生作用,随后通过激活蛋白激酶 C 激活腺苷酸环化酶或磷脂酶 C beta 等信号通路。PTH-rP 能够调节钙代谢并参与重要的发育过程,因此是研究和治疗应用的重要靶标。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

PTH-rP 抗体 (1D1) 参考文献:

  1. 每天使用人重组甲状旁腺激素-(1-34)LY333334治疗一年,可增加卵巢切除猴的骨量。  |  Brommage, R., et al. 1999. J Clin Endocrinol Metab. 84: 3757-63. PMID: 10523026
  2. 通过体外刺激源自前列腺癌转移的肿瘤浸润淋巴细胞,并使用装载有表位肽的自体树突状细胞和低剂量IL-2,诱导甲状旁腺激素相关蛋白(PTH-rP)特异性细胞毒性T细胞反应。  |  Correale, P., et al. 2001. Br J Cancer. 85: 1722-30. PMID: 11742494
  3. 通过细胞遗传学和分子研究绘制甲状旁腺激素基因(PTH)的区域图。  |  Tonoki, H., et al. 1991. Cytogenet Cell Genet. 56: 103-4. PMID: 1672845
  4. 从与恶性肿瘤体液性高钙血症相关的人类肿瘤中鉴定出编码甲状旁腺激素样肽的 cDNA。  |  Mangin, M., et al. 1988. Proc Natl Acad Sci U S A. 85: 597-601. PMID: 2829195
  5. 妊娠糖尿病并发症孕妇胎盘中 PTH-rP 和 PTH-R1 的表达:妊娠期高血糖病理生理学的新见解。  |  Sirico, A., et al. 2021. Diagnostics (Basel). 11: PMID: 34441291
  6. 一种与恶性高钙血症有关的甲状旁腺激素相关蛋白:克隆与表达。  |  Suva, LJ., et al. 1987. Science. 237: 893-6. PMID: 3616618
  7. 人体肿瘤合成肽与甲状旁腺激素在体内和体外的相似性。  |  Horiuchi, N., et al. 1987. Science. 238: 1566-8. PMID: 3685994
  8. 人类甲状旁腺激素:氨基末端,N端 1-34 位残基的氨基酸序列。  |  Brewer, HB., et al. 1972. Proc Natl Acad Sci U S A. 69: 3585-8. PMID: 4509319
  9. 分离人类甲状旁腺激素。  |  O'Riordan, JL., et al. 1971. Endocrinology. 89: 234-9. PMID: 5092521
  10. 甲状旁腺激素:合成和分泌的调节。  |  Watson, PH. and Hanley, DA. 1993. Clin Invest Med. 16: 58-77. PMID: 8467581
  11. PTH/PTHrP受体在早期发育和印度刺猬调节骨生长中的作用。  |  Lanske, B., et al. 1996. Science. 273: 663-6. PMID: 8662561
  12. 甲状旁腺激素相关蛋白与高钙血症  |  Rankin, W., et al. 1997. Cancer. 80: 1564-71. PMID: 9362423

订购信息

产品名称产品编号规格价格数量收藏夹

PTH-rP 抗体 (1D1)

sc-53936
200 µg/ml
$316.00

PTH-rP 抗体 (1D1) AC

sc-53936 AC
500 µg/ml, 25% agarose
$416.00

PTH-rP 抗体 (1D1) HRP

sc-53936 HRP
200 µg/ml
$316.00

PTH-rP 抗体 (1D1) FITC

sc-53936 FITC
200 µg/ml
$330.00

PTH-rP 抗体 (1D1) PE

sc-53936 PE
200 µg/ml
$343.00

PTH-rP 抗体 (1D1) Alexa Fluor® 488

sc-53936 AF488
200 µg/ml
$357.00

PTH-rP 抗体 (1D1) Alexa Fluor® 546

sc-53936 AF546
200 µg/ml
$357.00

PTH-rP 抗体 (1D1) Alexa Fluor® 594

sc-53936 AF594
200 µg/ml
$357.00

PTH-rP 抗体 (1D1) Alexa Fluor® 647

sc-53936 AF647
200 µg/ml
$357.00

PTH-rP 抗体 (1D1) Alexa Fluor® 680

sc-53936 AF680
200 µg/ml
$357.00

PTH-rP 抗体 (1D1) Alexa Fluor® 790

sc-53936 AF790
200 µg/ml
$357.00

can i use it for wb of ,mouse

Asked by: chennan
This antibody is currently only recommended for detection of PTH-rP of human origin.
Answered by: Technical Support
Date published: 2019-01-21

Can sc-53936: PTH-rP (1D1) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: Cweed
Thank you for your question. Yes, sc-53936: PTH-rP (1D1) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-24
  • y_2025, m_8, d_27, h_5CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_53936, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 106ms
  • QUESTIONS, PRODUCT
Rated 4 out of 5 by from On ELISAI received a sample of this antibody for use in ELISA ,but it don't work in E.coli, 1:100, got blank
Date published: 2017-07-31
Rated 5 out of 5 by from on WBI used 1:500 dilution, great antibody for WB, product nice specific signal
Date published: 2017-05-20
Rated 5 out of 5 by from Strong bandStrong band at the expected molecular weight for the human PTH-rP protein observed in WB using Hela cell.
Date published: 2017-03-05
Rated 5 out of 5 by from recommend for WBIt is a very specific antibody. I strongly recommend for WB.
Date published: 2017-02-25
Rated 5 out of 5 by from Use it to get a perfect result of WBAbout a month ago I bought this antibody and used it to make a Western blot dilution 1:500 I got a perfect result.
Date published: 2017-02-06
Rated 5 out of 5 by from antibody sampleI received a sample of this antibody for use in WB, It works great with human gastric carcinoma cells, It gives the appropriate molecular weight.
Date published: 2017-01-15
Rated 5 out of 5 by from greatUsed for human breast cancer cells. Immunoprecipitation experiments
Date published: 2017-01-15
Rated 5 out of 5 by from Positive western blot resultsWe used this antibody for western blot and got a positive band showing up
Date published: 2017-01-13
  • y_2025, m_8, d_27, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_9
  • loc_zh_CN, sid_53936, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 78ms
  • REVIEWS, PRODUCT
PTH-rP 抗体 (1D1) is rated 4.7 out of 5 by 9.
  • y_2025, m_8, d_27, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_9
  • loc_zh_CN, sid_53936, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 172ms
  • REVIEWS, PRODUCT