Prostaglandin F2alpha-d4 CAS: 34210-11-2
MF: C20H30D4O5
MW: 358.51
A PGF2αR activator.

Prostaglandin F2α-d4 (CAS 34210-11-2)

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备用名: PGF-d4; Dinoprost-d4
应用; Prostaglandin F2α-d4 is a PGF2αR activator
CAS号码: 34210-11-2
纯度: ≥99%
分子量: 358.51
分子式: C20H30D4O5
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).

Prostaglandin F2α-d4 (PGF2α-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. Prostaglandin F2α (PGF2α) is a widely distributed prostaglandin occurring in many species, shown to cause contraction of vascular, intestinal, bronchial, and myometrial smooth muscle. Additionally, prostaglandin F2α-d4 exerts potent luteolytic activity and activates PGF2αR.


参考文献

1. Samuelsson, B., et al., 1978. Prostaglandins and thromboxanes. Annual review of biochemistry. 47(): 997-1029. PMID: 209733
2. Watanabe, K., et al., 1986. Stereospecific conversion of prostaglandin D2 to (5Z,13E)-(15S)-9 alpha-11 beta,15-trihydroxyprosta-5,13-dien-1-oic acid (9 alpha,11 beta-prostaglandin F2) and of prostaglandin H2 to prostaglandin F2 alpha by bovine lung prostaglandin F synthase. Proceedings of the National Academy of Sciences of the United States of America. 83(6): 1583-7. PMID: 3456602
3. Speroff, L., et al., 1970. Prostaglandins in reproductive physiology. American journal of obstetrics and gynecology. 107(7): 1111-30. PMID: 4914185
4. Crankshaw, D J., et al., 1995. Pharmacological characterization in vitro of prostanoid receptors in the myometrium of nonpregnant ewes. Journal of reproduction and fertility. 103(1): 55-61. PMID: 7535849

规划 :
a solution in methyl acetate
外观 :
Solution
物理状态 :
Liquid
溶解度 :
Soluble in ethanol (~100 mg/ml), DMSO (~100 mg/ml), DMF (~100 mg/ml), and methyl acetate.
保存 :
Store at -20° C
沸点 :
57° C
仅供科研使用。不可用于诊断或治疗。
PubChem CID :
5283029
MDL 号码 :
MFCD00135271
SMILES :
[2H]C([2H])(CC(=O)O)C([2H])([2H])/C=C\\C[[email protected]]1[[email protected]](C[[email protected]]([[email protected]@H]1/C=C/[[email protected]](CCCCC)O)O)O

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