(±)-U-50488 hydrochloride CAS: 67197-96-0
(±)-U-50488 hydrochloride is a selective κ-opioid agonist.

(±)-U-50488 hydrochloride (CAS 67197-96-0)

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备用名: methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride
应用; (±)-U-50488 hydrochloride is a selective κ-opioid agonist
CAS号码: 67197-96-0
纯度: ≥98%
分子量: 811.58
分子式: (C19H26Cl2N2O•HCl)2
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).

(±)-U-50488 hydrochloride is a selective KOR (κ-opioid) agonist. (±)-U-50488 hydrochloride also blocks Na+ channels at higher concentrations. (±)-U-50488 hydrochloride is an inhibitor of Calcium Channel Protein.


参考文献

Suarez-Roca and Maixner (1983) Activation of kappa opioid receptors by U-50488H and morphine enhances the release of substance P from rat trigeminal nucleus slices. J.Pharmacol.Exp.Ther. 264 648. Pugsley et al (1992) Cardiovascular actions of the k-agonis

物理状态 :
Solid
溶解度 :
Soluble in water (25 mM).
保存 :
Desiccate at room temperature
仅供科研使用。不可用于诊断或治疗。
RTECS :
CY1484710
PubChem CID :
SMILES :
CN([[email protected]@H]1CCCC[[email protected]]1N2CCCC2)C(=O)CC3=CC(=C(C=C3)Cl)Cl.CN([[email protected]]1CCCC[[email protected]@H]1N2CCCC2)C(=O)CC3=CC(=C(C=C3)Cl)Cl.Cl.Cl

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