(+)-Cloprostenol (sodium salt) CAS: 62561-03-9
MF: C22H28ClO6Na
MW: 446.9
A synthetic analog of prostaglandin F2α.

(+)-Cloprostenol (sodium salt) (CAS 62561-03-9)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 95ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
备用名: D-Cloprostenol; (+)-16-m-chlorophenoxy tetranor PGF; (+)-16-m-chlorophenoxy tetranor Prostaglandin F
应用; A synthetic analog of prostaglandin F2α
CAS号码: 62561-03-9
分子量: 446.9
分子式: C22H28ClO6Na
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).

(+)-Cloprostenol (sodium salt) is a more water soluble, crystalline form of (+)-cloprostenol. (+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol accountable for the majority of its biological activity. Cloprostenol is 200 times and 100 times more potent than PGF2α in terminating pregnancy in hamsters and rats, respectively without the side effects associated with PGF2α. The subcutaneous dose required for interrupting early pregnancy is species dependent, requiring approximately 1.25 µg/kg and 270 µg/kg in hamsters and rats, respectively. Cloprostenol is also a potent inhibitor of rat adipose precursor differentiation in primary cultures with an IC50 of 3 x 10-12 M.


参考文献

1 Dukes, M., Russell, W., Walpole, A.L. Potent luteolytic agents related to prostaglandin F2α Nature 250, 330-331 (1974). 2 Serrero, G., Lepak, N.M. Prostaglandin F2α receptor (FP receptor) agonists are potent adipose differentiation inhibitors for primary culture of adipocyte precursors in defined medium. Biochem Biophys Res Commun 233 200-202 (1997).

物理状态 :
Solid
保存 :
Store at -20° C
仅供科研使用。不可用于诊断或治疗。
PubChem CID :
17756794
SMILES :
C1[[email protected]@H]([[email protected]@H]([[email protected]]([[email protected]@H]1O)/C=C/[[email protected]](COC2=CC(=CC=C2)Cl)O)C/C=C\\CCCC

下载SDS

分析证明书

在PDF文件上阅读,打印和批注,Adobe阅读器是必须的

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 104ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 6ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

圣克鲁斯生物技术在生物医药研究市场的产品开发方面处于世界领先地位。欢迎 致电我们的免费电话1-800-457-3801。 版权 ©, 2007-2020圣克鲁斯生物技术。版权所有。“Santa Cruz Biotechnology”,圣克鲁斯生物技 术的 商标,“Santa Cruz Animal Health”,“San Juan Ranch”,“Supplement of Champions”,San Juan Ranch的商标,“Ultracruz”,“Chemcruz”,“Immunocruz”,“Exactacruz”和“EZ Touch”都是圣克鲁斯生物技术的注册商标。所有的商标都归其各自拥有者所有。