Date published: 2025-9-6

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plexin-B1 抗体 (A-8): sc-28372

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说明书
  • plexin-B1 抗体 A-8 是小鼠单克隆 IgG2b κ,plexin-B1抗体, 在24篇文献中引用,规格为200 µg/ml
  • 免疫human物种的plexin-B1的氨基酸771-1070
  • plexin-B1 抗体 (A-8) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 plexin-B1
  • 抗plexin-B1抗体(A-8)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取plexin-B1 (A-8): sc-28372免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG2b BP-HRPm-IgGκ BP-HRP 是 plexin-B1 抗体 (A-8) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与plexin-B1 抗体 (A-8) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

plexin-B1抗体(A-8)是一种小鼠单克隆IgG2b kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)、免疫组织化学和酶联免疫吸附测定(ELISA)检测小鼠、大鼠和人类来源的plexin-B1。抗plexin-B1抗体(A- 8)有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种Alexa Fluor®结合物。plexin-B1在细胞信号传导通路中起着至关重要的作用,特别是在神经元发育和引导中,它充当 ,后者在胚胎发育和组织重塑过程中调节细胞运动和定位。plexin-B1与semaphorins相互作用,引导轴突发育并建立神经网络,因此plexin-B1对于正常神经系统的功能至关重要。plexin-B1还影响免疫反应和癌症进展,凸显了plexin-B1在健康和疾病中的重要性。了解plexin-B1的功能和信号传导机制有助于深入了解神经疾病和癌症治疗的治疗靶点。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

plexin-B1 抗体 (A-8) 参考文献:

  1. Plexin-neuropilin-1 复合物形成功能性 semaphorin-3A 受体。  |  Takahashi, T., et al. 1999. Cell. 99: 59-69. PMID: 10520994
  2. 在脊椎动物中,Plexins 是跨膜, 分泌和 GPI-anchored semaphorins 受体的一个大家族。  |  Tamagnone, L., et al. 1999. Cell. 99: 71-80. PMID: 10520995
  3. Plexin-B1和Plexin-B2与Rnd家族蛋白相互作用的分析。  |  Wylie, T., et al. 2017. PLoS One. 12: e0185899. PMID: 29040270
  4. Plexin-B1突变驱动前列腺癌小鼠模型的转移。  |  Shorning, B., et al. 2023. Cancer Res Commun. 3: 444-458. PMID: 36936664
  5. Plexin-B1的纳米抗体抑制剂可识别Plexin-Semaphorin相互作用和信号传导中的异构体。  |  Cowan, R., et al. 2023. J Biol Chem. 299: 104740. PMID: 37088134
  6. Plexin-B1和Plexin-B2在GABA能突触形成中发挥非冗余作用。  |  Adel, SS., et al. 2024. Mol Cell Neurosci. 128: 103920. PMID: 38331011
  7. Plexin-B1对斑块周围胶质网中细胞距离的调节会影响阿尔茨海默氏症中的胶质激活和淀粉样蛋白的压缩。  |  Huang, Y., et al. 2024. Nat Neurosci. 27: 1489-1504. PMID: 38802590
  8. semaphorin基因编码一系列跨膜和分泌型生长锥导向分子。  |  Kolodkin, AL., et al. 1993. Cell. 75: 1389-99. PMID: 8269517
  9. 鉴定小鼠中的丛神经蛋白家族分子。  |  Kameyama, T., et al. 1996. Biochem Biophys Res Commun. 226: 396-402. PMID: 8806646
  10. 肝细胞生长因子(HGF)和相关散射因子对侵入性生长的控制。  |  Tamagnone, L. and Comoglio, PM. 1997. Cytokine Growth Factor Rev. 8: 129-42. PMID: 9244408
  11. Plexin A 是一种控制轴突导向的神经元半影素受体。  |  Winberg, ML., et al. 1998. Cell. 95: 903-16. PMID: 9875845
  12. Plexins, semaphorins和散射因子受体:细胞引导信号的共同根源?  |  Artigiani, S., et al. 1999. IUBMB Life. 48: 477-82. PMID: 10637762

订购信息

产品名称产品编号规格价格数量收藏夹

plexin-B1 抗体 (A-8)

sc-28372
200 µg/ml
$316.00

plexin-B1 (A-8): m-IgGκ BP-HRP 套装

sc-520813
200 µg Ab, 40 µg BP
$354.00

plexin-B1 (A-8): m-IgG2b BP-HRP 套装

sc-548854
200 µg Ab; 10 µg BP
$354.00

plexin-B1 抗体 (A-8) AC

sc-28372 AC
500 µg/ml, 25% agarose
$416.00

plexin-B1 抗体 (A-8) HRP

sc-28372 HRP
200 µg/ml
$316.00

plexin-B1 抗体 (A-8) FITC

sc-28372 FITC
200 µg/ml
$330.00

plexin-B1 抗体 (A-8) PE

sc-28372 PE
200 µg/ml
$343.00

plexin-B1 抗体 (A-8) Alexa Fluor® 488

sc-28372 AF488
200 µg/ml
$357.00

plexin-B1 抗体 (A-8) Alexa Fluor® 546

sc-28372 AF546
200 µg/ml
$357.00

plexin-B1 抗体 (A-8) Alexa Fluor® 594

sc-28372 AF594
200 µg/ml
$357.00

plexin-B1 抗体 (A-8) Alexa Fluor® 647

sc-28372 AF647
200 µg/ml
$357.00

plexin-B1 抗体 (A-8) Alexa Fluor® 680

sc-28372 AF680
200 µg/ml
$357.00

plexin-B1 抗体 (A-8) Alexa Fluor® 790

sc-28372 AF790
200 µg/ml
$357.00

Can I use this mouse monoclonal antibody for immunohistochemical staining of mouse tissue? Or even double or triple staining on the same samples?

Asked by: DefinitelyNotMatt
Thank you for your question. Yes. We recommend using a directly conjugated mouse monoclonal primary antibody. This antibody is currently available conjugated to phycoerythrin (sc-28372 PE), fluorescein (sc-28372 FITC), Alexa Fluor® 488 (sc-28372 AF488) or Alexa Fluor® 647 (sc-28372 AF647). Please contact Technical Service if you have further questions concerning this product.
Answered by: Technical Support 7
Date published: 2019-12-26
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Rated 5 out of 5 by from antibody appied in FCM? any experience ?Can this antibody be used for flow analysis, and is there any experience to share
Date published: 2024-03-12
Rated 5 out of 5 by from clear bandWe observed clear band when diluted 1:500 ,Great help to us, strongly recommended.
Date published: 2017-05-28
Rated 4 out of 5 by from good for detection of rat plexin-B1 by WBused this antibody for immunoblotting of rat retina lysates, it gave clean bands at the expected molecular size.
Date published: 2017-05-24
Rated 5 out of 5 by from Pretty goodGet good results with it in IF and WB, strong signal low background
Date published: 2017-05-23
Rated 5 out of 5 by from Very popular choice!sc-28372 is a very popular choice for detection of plexin-B1 by Western blot and IHC(P).
Date published: 2016-12-22
Rated 5 out of 5 by from Published data for WB in human WTPublished data for WB in human WT, Sema4D TAM, TSA, and MLP29 cells. -SCBT Publication Review
Date published: 2015-05-24
Rated 5 out of 5 by from Published data for WB in human umbilicalPublished data for WB in human umbilical vein endothelial cells. -SCBT Publication Review
Date published: 2015-05-05
Rated 5 out of 5 by from Excellent immunoperoxidase cytoplasic stainingExcellent immunoperoxidase cytoplasic staining in formalin fixed, paraffin-embedded human duodenum tissue. -SCBT QC
Date published: 2015-03-21
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plexin-B1 抗体 (A-8) is rated 4.9 out of 5 by 11.
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