Date published: 2025-9-8
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plasminogen Antibody (10A1) - Western Blotting - Image 62797
plasminogen (10A1): sc-69793. 从人血浆 (A) 和人血浆 (B) 中纯化的纤溶酶原的 Western 印迹分析.
plasminogen Antibody (10A1) - Western Blotting - Image 62797
plasminogen (10A1): sc-69793. 从人血浆 (A) 和人血浆 (B) 中纯化的纤溶酶原的 Western 印迹分析.
plasminogen (10A1): sc-69793. 从人血浆 (A) 和人血浆 (B) 中纯化的纤溶酶原的 Western 印迹分析.

plasminogen 抗体 (10A1): sc-69793

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说明书
  • plasminogen 抗体 10A1 是小鼠单克隆 IgG1, 在2篇文献中引用，提供 100 µl
  • 针对纯化的plasminogen human 起源
  • 推荐用于 mouse, rat 和 human 来源的plasminogen WB, IP 和 ELISA检测
  • 目前，我们还没有完成plasminogen 抗体 (10A1)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

纤溶酶原丝氨酸蛋白酶裂解形成纤溶酶是纤溶系统溶解血栓的核心过程。在纤溶级联反应中，尿激酶型纤溶酶原激活物（uPA）和组织型纤溶酶原激活物（tPA）等丝氨酸蛋白酶通过裂解纤溶酶原激活纤溶酶原前体，从而形成具有纤溶活性的纤溶酶。纤溶酶由561个氨基酸的重链和230个氨基酸残基的轻链组成，前者来自纤溶酶原的N端，后者来自纤溶酶原的C端。纤溶酶是一种促血管生成蛋白酶，能够降解多种细胞外基质蛋白，促进内皮细胞迁移和血管生成。在游离巯基供体（FSD）存在下，纤溶酶发生自溶并被转化为血管抑素酶，后者可阻断血管生成和新血管形成，抑制原发性和转移性肿瘤的生长。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

plasminogen 抗体 (10A1) 参考文献:

  1. 胶浆纤溶酶原转化为赖氨酸纤溶酶原对细胞表面纤溶酶原活化的最佳刺激起着关键作用。  |  Miles, LA., et al. 2003. Trends Cardiovasc Med. 13: 21-30. PMID: 12554097
  2. 在体外纤维蛋白溶解过程中，Lys-plasminogen 是激活 Glu-plasminogen 的重要中间体。  |  Fredenburgh, JC. and Nesheim, ME. 1992. J Biol Chem. 267: 26150-6. PMID: 1464625
  3. 卵巢生理学中的血浆酶原激活剂/血浆酶原激活剂抑制剂。  |  Liu, YX. 2004. Front Biosci. 9: 3356-73. PMID: 15353363
  4. 细菌纤溶酶原受体利用宿主纤溶酶原系统进行有效入侵和传播。  |  Bhattacharya, S., et al. 2012. J Biomed Biotechnol. 2012: 482096. PMID: 23118509
  5. 血浆蛋白酶原能促进小鼠巨噬细胞的吞噬作用。  |  Das, R., et al. 2014. Blood. 124: 679-88. PMID: 24876560
  6. 从纤溶酶原到纤溶酶：纤溶酶原受体在人类癌症中的作用。  |  Didiasova, M., et al. 2014. Int J Mol Sci. 15: 21229-52. PMID: 25407528
  7. 纤溶酶原激活剂的纳米脂质体载体。  |  Koudelka, S., et al. 2016. J Control Release. 227: 45-57. PMID: 26876783
  8. 多胎妊娠可上调胎盘纤溶酶原和尿激酶型纤溶酶原激活剂。  |  Cortina, ME., et al. 2017. Am J Reprod Immunol. 77: PMID: 28158911
  9. 神经血管和神经退行性疾病中的血浆酶原激活剂。  |  Yepes, M., et al. 2021. Int J Mol Sci. 22: PMID: 33922229
  10. 用凝血酶原眼药水治疗结膜炎  |  Caputo, R., et al. 2022. Ophthalmology. 129: 955-957. PMID: 35346720

订购信息

产品名称产品编号规格价格数量收藏夹

plasminogen 抗体 (10A1)

sc-69793
100 µl
$316.00

What is the concentration of plasminogen (10A1): sc-69793 monoclonal antibody?

Asked by: Germaine
Thank you for your question. The concentration of plasminogen (10A1): sc-69793 has not been characterized. We provide 100 µl of this antibody
Answered by: Technical Support
Date published: 2017-03-24
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Rated 4 out of 5 by from Great for WB!This AB gives one clean appropriate size band in Hek and HeLa lysate. It gives two bands in embryonic chick spinal cord tissue (corresponding to the different isoforms). Extremely clean!
Date published: 2018-03-13
Rated 4 out of 5 by from Nice bands seen in WB using plasminogen purifiedNice bands seen in WB using plasminogen purified from human plasma and in human plasma. -SCBT QC
Date published: 2015-04-13
Rated 4 out of 5 by from This antibody was used in a publication forThis antibody was used in a publication for ELISA on human fibrinogen - SCBT Publication Review
Date published: 2015-02-20
Rated 4 out of 5 by from WB publishable data with human marrowWB publishable data with human marrow-derived stromal cells - SCBT Publication Review
Date published: 2013-08-31
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plasminogen 抗体 (10A1) is rated 4.0 out of 5 by 4.
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