PKSI-527 (CAS 128837-71-8)

5.0(1)

写一个评价提问

查看产品引用文献(3)

备用名: trans-4-Aminomethylcyclohexanecarbonyl-phenylalanyl-4-carboxymethylanilide

应用； PKSI-527 is a highly selective plasma kalikrein inhibitor that can be used for affinity purification of kalikrein

CAS号码: 128837-71-8

纯度: ≥95%

分子量: 473.99

分子式: C₂₅H₃₁N₃O₄•HCl

仅供科研使用。不可用于诊断或治疗。

* 参考分析证明大量特定数据 (包括水含量).

快捷链接

点击图片或放大按钮来放大

PKSI-527 is a highly selective plasma kallikrein inhibitor (K_i = 0.81 μM) which can be used for affinity purification of kalikrein. It suppresses collagen-induced arthritis in a mouse model. Additionally, PKSI-527 has been shown to synergize with NO donors producing antithrombotic effects.

参考文献

1: K. Wanaka et al. Chem. Pharm. Bull. 1992 40 1814 2: M. Tada et al. Biol. Pharm. Bull. 2001 24 520 3: Y. Fujimori et al. Agents Actions 1993 39 42 4: H. Ikarugi et al. Thromb. Res. 2005 116 403

物理状态 :

Solid

溶解度 :

Soluble in water (5 mg/ml).

保存 :

Store at -20° C

Ki 数据 :

selective plasma kalikrein: K_i= 0.81 µM

仅供科研使用。不可用于诊断或治疗。

PubChem CID :

3035562

SMILES :

C1CC(CCC1CN)C(=O)N[[email protected]@H](CC2=CC=CC=C2)C(=O)NC3=CC=C(C=C3)CC(=O)O.Cl

下载SDS

分析证明书

在PDF文件上阅读，打印和批注，Adobe阅读器是必须的