Pitavastatin Lactone CAS: 141750-63-2
MF: C25H22FNO3
MW: 403.45
A major phase 2 metabolite of pitavastatin, an inhibitor of HMG-CoA reductase.

Pitavastatin Lactone (CAS 141750-63-2)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 100ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Pitavastatin Lactone is rated 5.0 out of 5 by 1.
5
1
4
0
3
0
2
0
1
0
应用; Pitavastatin Lactone is a major phase 2 metabolite of pitavastatin, an inhibitor of HMG-CoA reductase
CAS号码: 141750-63-2
纯度: ≥95%
分子量: 403.45
分子式: C25H22FNO3
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).

Pitavastatin Lactone is a major phase 2 metabolite of pitavastatin, an inhibitor of HMG-CoA reductase. Studies have shown that conversion between the acid and lactone forms of pitavastatin occurs in the body and that these two forms differ in substrate activity tow.


参考文献

1. Miners, J.O., et al. 2002. Toxicology 181: 453-456. PMID: 12505351
2. Prueksaritanont, T., et al. 2002. Drug Metab. Dispos. 30: 505-512. PMID: 11950779
3. Benet, L.Z., et al. 2003. Curr. Drug Metab. 4: 393-398. PMID: 14529371
4. Lin, J., et al. 2003. Clin. Pharmacokinet. 42: 59-98. PMID: 12489979
5. Fujino, H., et al. 2004. Xenobiotica. 34: 961-971. PMID: 15801541
6. Yamada, I., et al. 2003. Xenobiotica. 33: 789-803. PMID: 12893526
7. Tian, L., et al. 2008. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 865: 127-132. PMID: 18342583

外观 :
Powder
物理状态 :
Solid
保存 :
Store at -20° C
仅供科研使用。不可用于诊断或治疗。
PubChem CID :
9801294
SMILES :
OC1C[[email protected]](OC(=O)C1)\\C=C\\C1=C(C2=CC=C(F)C=C2)C2=CC=CC=C2N=C1C1CC1

下载SDS

分析证明书

在PDF文件上阅读,打印和批注,Adobe阅读器是必须的

Pitavastatin Lactone (CAS 141750-63-2)  产品相关文献索引

看其他用户如何应用Pitavastatin Lactone (CAS 141750-63-2).点击进入浏览PubMed条目 .

引用1 - 11

PMID: # 25318994  Hosaka, S. et al. 2015. Drug Metab. Dispos. 43: 27-33.

引用1 - 11
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 146ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 6ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

圣克鲁斯生物技术在生物医药研究市场的产品开发方面处于世界领先地位。欢迎 致电我们的免费电话(021) 800-820-8626。 版权 ©, 2007-2021圣克鲁斯生物技术。版权所有。“Santa Cruz Biotechnology”,圣克鲁斯生物技 术的 商标,“Santa Cruz Animal Health”,“San Juan Ranch”,“Supplement of Champions”,San Juan Ranch的商标,“Ultracruz”,“Chemcruz”,“Immunocruz”,“Exactacruz”和“EZ Touch”都是圣克鲁斯生物技术的注册商标。所有的商标都归其各自拥有者所有。