Molecular structure of PHCCC
PHCCC
Application:
PHCCC is a group I metabotropic glutamate receptor antagonist
Molecular Weight:
294.30
Molecular Formula:
C17H14N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
PHCCC has been shown to act as a group I metabotropic glutamate receptor antagonist with an IC50 of approximately 3 µM. This activity is 67 times more potent than (S)-4-carboxyphenylglycine (sc-203449). This compound has also demonstrated positive allosteric modulation for mGlu4a, potentiates L-AP4-mediated inhibition of striatopallidal synaptic transmission in vitro, and displays anti-Parkinsonian effects in rat models.
Inhibitor of:
mGluR-1a, mGluR-1b, and mGluR-5.Activator of:
mGluR-4.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PHCCC, 10 mg | sc-361292 | 10 mg | $145.00 | |||
PHCCC, 50 mg | sc-361292A | 50 mg | $615.00 |