Date published: 2025-9-10

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PGE synthase 抗体 (B-6): sc-166309

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说明书
  • PGE synthase抗体(B-6)是小鼠单克隆IgG1 κ, 在1篇文献中引用,规格为200 µg/ml
  • 免疫human物种的代表全长PGE synthase的氨基酸1-152
  • 推荐用于 human 来源的PGE synthase WB, IP, IF, IHC(P) 和 ELISA检测
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 是 PGE synthase 抗体 (B-6) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与PGE synthase 抗体 (B-6) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

前列腺素E合酶(PGE合酶),也称为PIG12和MGST1-L1,是MAPEG蛋白质超家族的成员,由参与二十烷类和谷胱甘肽代谢的膜相关蛋白组成。这种膜相关蛋白的表达可由促炎细胞因子IL-1β诱导。PGE合酶在精囊、输精管、肾、心和脾中表达。大多数器官中PGE合酶的酶活性依赖于谷胱甘肽。PGE合酶可能在阿尔茨海默病的进展中发挥重要作用。人类PGE合酶定位于9号染色体q34区。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

PGE synthase 抗体 (B-6) 参考文献:

  1. 前列腺素 E 合酶,前列腺素 E2 生物合成的终止子。  |  Kudo, I. and Murakami, M. 2005. J Biochem Mol Biol. 38: 633-8. PMID: 16336776
  2. 微粒体前列腺素 E 合酶-1 和 5-脂氧合酶:癌症的潜在药物靶点。  |  Rådmark, O. and Samuelsson, B. 2010. J Intern Med. 268: 5-14. PMID: 20497297
  3. 微粒体前列腺素 E 合酶-1 可防止 Fas 引起的肝损伤。  |  Yao, L., et al. 2016. Am J Physiol Gastrointest Liver Physiol. 310: G1071-80. PMID: 27102561
  4. 微粒体前列腺素 E 合酶-1 和 PGE2 受体在心血管健康和疾病中的最新进展。  |  Yang, G. and Chen, L. 2016. Oxid Med Cell Longev. 2016: 5249086. PMID: 27594972
  5. 抑制微粒体前列腺素 E 合酶-1 有助于小鼠肝损伤后的肝脏修复。  |  Nishizawa, N., et al. 2018. J Hepatol. 69: 110-120. PMID: 29458169
  6. 抑制癌症相关成纤维细胞微粒体前列腺素 E 合酶-1 可抑制神经母细胞瘤肿瘤生长  |  Kock, A., et al. 2018. EBioMedicine. 32: 84-92. PMID: 29804818
  7. mPGES-1(微粒体前列腺素 E 合酶-1)通过氧化应激介导高血压的血管功能障碍。  |  Avendaño, MS., et al. 2018. Hypertension. 72: 492-502. PMID: 29891646
  8. 微粒体前列腺素 E 合酶-1 基因缺失可抑制化学诱导的皮肤癌发生  |  Sasaki, Y., et al. 2021. Anticancer Res. 41: 1307-1314. PMID: 33788722
  9. 结肠癌中诱导性微粒体前列腺素 E 合酶-1 对前列腺素 E2 的上调作用。  |  Kim, YH. and Kim, KJ. 2022. Ann Coloproctol. 38: 153-159. PMID: 34465013
  10. 微粒体前列腺素 E 合酶-1 参与了与肥胖相关的代谢和心血管改变。  |  Ballesteros-Martínez, C., et al. 2022. Br J Pharmacol. 179: 2733-2753. PMID: 34877656

订购信息

产品名称产品编号规格价格数量收藏夹

PGE synthase 抗体 (B-6)

sc-166309
200 µg/ml
$316.00

PGE synthase (B-6): m-IgG Fc BP-HRP 套装

sc-540073
200 µg Ab; 10 µg BP
$354.00

PGE synthase (B-6): m-IgG1 BP-HRP 套装

sc-541889
200 µg Ab; 20 µg BP
$354.00

I am using PGE synthase (B-6): sc-166309 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Asked by: Randy McDonald
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from clear band obtainedI use sc-166309 detect rheumatoid arthritis synovium tissue,which some studies shows the expression ,dilution 1:400 been used,clear band obtained
Date published: 2017-06-14
Rated 5 out of 5 by from strong signalI used it for IF on HeLa cells (1:400 dilution). It works both on PFA and methanol-fixed cells,strong signal.
Date published: 2017-05-31
Rated 5 out of 5 by from Great immunoperoxidase cytoplasmic stainingGreat immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human placenta tissue. -SCBT QC
Date published: 2015-05-21
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PGE synthase 抗体 (B-6) is rated 5.0 out of 5 by 4.
  • y_2025, m_8, d_28, h_5
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