Date published: 2025-9-8

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PGE synthase 抗体 (A-3): sc-166308

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说明书
  • PGE synthase 抗体 A-3 是小鼠单克隆 IgG1 κ,PGE synthase抗体, 在7篇文献中引用,规格为200 µg/ml
  • 免疫human物种的代表全长PGE synthase的氨基酸1-152
  • PGE synthase 抗体 (A-3) 推荐用于WB, IP, IF, IHC(P) 和 ELISA,检测human 来源的 PGE synthase
  • 抗PGE synthase抗体(A-3)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取PGE synthase (A-3): sc-166308免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRPm-IgGκ BP-HRP 是 PGE synthase 抗体 (A-3) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与PGE synthase 抗体 (A-3) 组合成套装提供。 (请参阅下面的订购信息)。

快捷链接

関連項目

PGE合酶抗体(A-3)是一种IgG1 κ小鼠单克隆PGE合酶抗体(也称为PGE合酶抗体),可通过WB、IP、IF、IHC(P)和ELISA检测人源PGE合酶蛋白。PGE合酶抗体(A-3)既可以是非偶联的抗PGE合酶抗体形式,也可以是多种偶联形式的抗PGE合酶抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。前列腺素E合酶(PGE合酶),也称为PIG12和MGST1-L1,是MAPEG蛋白质超家族的成员,由参与二十烷类和谷胱甘肽代谢的膜相关蛋白组成。这种膜相关蛋白的表达可由促炎细胞因子IL-1β诱导。PGE合酶在精囊、输精管、肾、心和脾中表达。大多数器官中PGE合酶的酶活性依赖于谷胱甘肽。PGE合酶可能在阿尔茨海默病的进展中发挥重要作用。人类PGE合酶定位于9号染色体q34区。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

PGE synthase 抗体 (A-3) 参考文献:

  1. 微粒体前列腺素 E 合酶 1 抑制剂的特征。  |  Korotkova, M. and Jakobsson, PJ. 2014. Basic Clin Pharmacol Toxicol. 114: 64-9. PMID: 24138533
  2. 抑制微粒体前列腺素 E 合酶-1 作为癌症治疗的靶向疗法。  |  Larsson, K. and Jakobsson, PJ. 2015. Prostaglandins Other Lipid Mediat. 120: 161-5. PMID: 26100239
  3. 微粒体前列腺素 E 合酶-1(mPGES-1)产生的前列腺素 E2 在结肠癌发生中的作用。  |  Sasaki, Y., et al. 2015. Prostaglandins Other Lipid Mediat. 121: 42-5. PMID: 26150361
  4. 微粒体前列腺素 E 合酶-1 是帕金森病多巴胺能神经变性的关键因素。  |  Ikeda-Matsuo, Y., et al. 2019. Neurobiol Dis. 124: 81-92. PMID: 30423474
  5. 以微粒体前列腺素 E 合酶 1 为靶点,开发治疗炎症性疾病的药物。  |  Wang, Q., et al. 2021. Am J Transl Res. 13: 391-419. PMID: 33527033
  6. 诱导性前列腺素 E 合酶作为缺血性中风的药理靶点。  |  Li, L., et al. 2022. Neurotherapeutics. 19: 366-385. PMID: 35099767
  7. 癫痫状态后对微粒体前列腺素 E 合酶-1 的短暂抑制可减轻脑部炎症并具有神经保护作用。  |  Yasmen, N., et al. 2023. Mol Brain. 16: 14. PMID: 36694204
  8. 微粒体前列腺素 E 合成酶-1 和-2:非酒精性脂肪肝的新靶点  |  Kotsos, D. and Tziomalos, K. 2023. Int J Mol Sci. 24: PMID: 36769370
  9. 抑制微粒体前列腺素 E 合酶-1 可预防小鼠心肌梗死后心脏重塑的不良后果。  |  Zhang, Y., et al. 2023. Br J Pharmacol. 180: 1981-1998. PMID: 36788645
  10. 神经炎性疾病中的诱导性前列腺素 E 合酶(mPGES-1)。  |  Sluter, MN., et al. 2023. Exp Biol Med (Maywood). 248: 811-819. PMID: 37515545

订购信息

产品名称产品编号规格价格数量收藏夹

PGE synthase 抗体 (A-3)

sc-166308
200 µg/ml
$316.00

PGE synthase (A-3): m-IgG Fc BP-HRP 套装

sc-528941
200 µg Ab; 10 µg BP
$354.00

PGE synthase (A-3): m-IgGκ BP-HRP 套装

sc-521563
200 µg Ab, 40 µg BP
$354.00

PGE synthase (A-3): m-IgG1 BP-HRP 套装

sc-543226
200 µg Ab; 20 µg BP
$354.00

PGE synthase 抗体 (A-3) AC

sc-166308 AC
500 µg/ml, 25% agarose
$416.00

PGE synthase 抗体 (A-3) HRP

sc-166308 HRP
200 µg/ml
$316.00

PGE synthase 抗体 (A-3) FITC

sc-166308 FITC
200 µg/ml
$330.00

PGE synthase 抗体 (A-3) PE

sc-166308 PE
200 µg/ml
$343.00

PGE synthase 抗体 (A-3) Alexa Fluor® 488

sc-166308 AF488
200 µg/ml
$357.00

PGE synthase 抗体 (A-3) Alexa Fluor® 546

sc-166308 AF546
200 µg/ml
$357.00

PGE synthase 抗体 (A-3) Alexa Fluor® 594

sc-166308 AF594
200 µg/ml
$357.00

PGE synthase 抗体 (A-3) Alexa Fluor® 647

sc-166308 AF647
200 µg/ml
$357.00

PGE synthase 抗体 (A-3) Alexa Fluor® 680

sc-166308 AF680
200 µg/ml
$357.00

PGE synthase 抗体 (A-3) Alexa Fluor® 790

sc-166308 AF790
200 µg/ml
$357.00

I am using PGE synthase (A-3): sc-166308 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Asked by: Cweed
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from good antibodyantibody (1:500 dilution) works good in HEK cell line
Date published: 2018-09-05
Rated 4 out of 5 by from Worked nicelyThis antibody worked nicely. I ran my samples on a 12% gel and did a 1:300 dilution with a 1:5000 secondary. Nice and clear!.
Date published: 2017-10-10
Rated 5 out of 5 by from Excellent!The antibody is very strong and highly specific in Western blot application
Date published: 2017-05-05
Rated 4 out of 5 by from no signal in decidual macrophagesI have not detect signal in human decidual macrophages by WB, and it maybe caused by low expression in these cells.
Date published: 2016-12-06
Rated 5 out of 5 by from Produced excellent immunoperoxidase cytoplasmicProduced excellent immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human testis tissue. -SCBT QC
Date published: 2015-02-09
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PGE synthase 抗体 (A-3) is rated 4.7 out of 5 by 6.
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