Date published: 2025-9-7

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Peroxin 5 抗体 (B-9): sc-365629

5.0(2)
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说明书
  • Peroxin 5抗体(B-9)是小鼠单克隆IgG2b (kappa轻链),规格为200 µg/ml
  • 特异性抗原位于human物种的Peroxin 5的内部区域内的氨基酸127-154之间
  • 推荐用于 mouse, rat 和 human 来源的Peroxin 5 WB, IP, IF, IHC(P) 和 ELISA检测; 也和以下物种反应,包括: 和 equine, canine and porcine
  • m-IgG2b BP-HRP 是Peroxin 5 抗体 (B-9) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与Peroxin 5 抗体 (B-9) 组合成套装提供。 (请参阅下面的订购信息)。

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    过氧化物酶体是存在于几乎所有真核细胞中的单膜结合细胞器。它们参与许多分解代谢和合成代谢途径,包括长链脂肪酸的β-氧化、过氧化氢代谢、缩醛磷脂生物合成和胆汁酸合成。过氧化物酶基因家族包括20多个成员,是过氧化物酶体生物发生所必需的。该家族的两个成员,过氧化物酶5(Pex5)和过氧化物酶7(Pex7),分别是含有过氧化物酶体靶向信号1(PTS1)和2(PTS2)的蛋白质的受体,并将这些蛋白质从细胞溶质转运到过氧化物酶体。过氧化物酶5,也称为PTS1受体,以两种异构体Pex5L和Pex5S的形式表达。Pex5L将PTS1和Pex7-PTS2货物复合物转运到初始Pex5停靠位点Pex14,而Pex5S仅转运PTS1货物。过氧化物酶5和过氧化物酶7还需要与过氧化物酶13(Pex13)直接或间接相互作用才能正确导入过氧化物酶体。过氧化物酶基因突变导致过氧化物酶体生物发生障碍(PBD)。Pex5基因缺陷与补体组2(CG2)的Zellweger综合征(脑-肝-肾综合征)有关,这是最严重的PBD形式。Zellweger综合征的特征是中枢神经系统神经元迁移异常和严重的神经功能障碍,导致早逝。

    仅限研究使用。不适用于诊断和治疗用途。

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Peroxin 5 抗体 (B-9)

    sc-365629
    200 µg/ml
    $316.00

    Peroxin 5 (B-9): m-IgG2b BP-HRP 套装

    sc-548559
    200 µg Ab; 10 µg BP
    $354.00

    Peroxin 5 (B-9) 中和勝肽

    sc-365629 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-365629 P appropriate for?

    Asked by: Randy McDonald
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-28
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    Rated 5 out of 5 by from Good specificity and signal strength in humanGood specificity and signal strength in human Peroxin 5 transfected 293T whole cell lysate. -SCBT QC
    Date published: 2015-05-06
    Rated 5 out of 5 by from Produced exceptional immunoperoxidase cytoplasmicProduced exceptional immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human skin tissue. -SCBT QC
    Date published: 2015-04-23
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    Peroxin 5 抗体 (B-9) is rated 5.0 out of 5 by 2.
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